Research Article

Antithrombotic Therapy in Patients with Acute Coronary Syndrome in the Intermountain Heart Collaborative Study

Table 2

Patient characteristics by in-hospital AT therapy.

No Antiplatelet Single antiplatelet Dual antiplatelet
No ACACNo ACACNo ACAC

Age (mean ± std)63.8 ± 13.4863.1 ± 15.2568.4 ± 16.8764.7 ± 12.5066.9 ± 10.9364.1 ± 12.25
Male37.5%67.9%58.3%68.4%80.0%74.2%
Caucasian87.5%91.7%91.7%88.2%100.0%89.7%
Body Mass Index (mean ± std)29.5 ± 4.1828.9 ± 6.2927.4 ± 5.9330.0 ± 10.0432.2 ± 7.4429.7 ± 7.55
Family history of early CVD50.0%36.7%33.3%39.7%40.0%45.3%
Smoking history 25.0%13.8%16.7%15.2%10.0%16.4%
Prior MI25.0%7.3%0.0%13.8%0.0%17.5%
Comorbidities
 COPD0.0%8.3%25.0%7.6%0.0%7.5%
 CVA0.0%5.5%8.3%5.1%0.0%3.8%
 Diabetes 12.5%21.1%16.7%26.5%30.0%25.9%
 Heart failure 25.0%25.7%33.3%31.8%10.0%22.6%
 Hypercoagulability 0.0%0.9%0.0%0.4%0.0%0.1%
 Hyperlipidemia 37.5%57.8%58.3%60.3%50.0%66.2%
 Hypertension50.0%65.1%75.0%62.6%90.0%66.0%
 Major bleeding or ICH0.0%2.8%8.3%2.8%0.0%1.9%
 Renal failure0.0%7.3%0.0%8.2%20.0%6.4%
 Valve disease0.0%11.9%0.0%9.2%10.0%9.0%
 VTE0.0%9.2%0.0%9.1%10.0%5.7%
AF
 No AF75.0%81.7%58.3%72.5%90.0%85.1%
 Prior but not current12.5%6.4%16.7%3.8%0.0%4.2%
 Prior and current0.0%8.3%0.0%6.6%10.0%4.2%
 New onset12.5%3.7%25.0%17.1%0.0%6.5%
Charlson Comorbidity Index (mean ± std)5.6 ± 3.746.0 ± 3.728.2 ± 5.026.5 ± 4.056.6 ± 5.605.9 ± 3.82
Mechanical value0.0%0.0%0.0%0.5%0.0%0.2%
Presentation
 Unstable angina25.0%65.1%41.7%44.2%20.0%40.0%
 STEMI0.0%9.2%16.7%8.2%30.0%14.6%
 Non-STEMI75.0%25.7%41.7%47.6%50.0%45.4%
In-hospital procedures
 PCI without stent0.0%4.6%0.0%6.1%0.0%5.3%
 PCI with bare metal stent0.0%8.3%0.0%2.5%20.0%27.2%
 PCI with drug eluting stent0.0%14.7%0.0%6.8%60.0%58.4%
 CABG0.0%11.0%8.3%39.0%0.0%2.9%
Number of vessels with CAD
 None50.0%33.0%33.3%22.4%10.0%3.9%
 Single12.5%25.7%16.7%18.7%50.0%42.0%
 Multiple37.5%41.3%50.0%58.9%40.0%54.1%
Hospital length of stay (mean ± std)10.8 ± 7.144.8 ± 6.463.0 ± 1.917.3 ± 7.862.2 ± 1.403.4 ± 4.54

Note: AC: anticoagulant; CVD: cardiovascular disease; MI: myocardial infarction; COPD: chronic obstructive pulmonary disease; CVA: cerebral vascular accident; ICH: intracranial hemorrhage; VTE: vascular thrombus event; AF: atrial fibrillation; STEMI: ST elevated myocardial infarction; PCI: percutaneous coronary intervention; CABG: coronary artery bypass graph; CAD: coronary artery disease.