Research Article

Antithrombotic Therapy in Patients with Acute Coronary Syndrome in the Intermountain Heart Collaborative Study

Table 3

Patient characteristics by postdischarge AT therapy.

No antiplatelet Single antiplatelet Dual antiplatelet
No ACACNo ACACNo ACAC

Age (mean ± std)64.9 ± 15.1867.6 ± 12.7664.3 ± 12.2967.7 ± 11.9863.8 ± 12.2667.8 ± 12.50
Male61.2%69.6%70.7%66.5%73.7%76.6%
Caucasian94.2%91.3%87.9%90.5%89.5%92.3%
Body Mass Index (mean ± std)28.2 ± 5.9730.6 ± 8.8629.9 ± 7.2730.2 ± 18.3929.7 ± 6.8130.6 ± 13.87
Family history of early CVD31.1%17.4%43.7%37.4%45.5%37.0%
Smoking history 8.7%26.1%16.0%12.8%16.3%17.2%
Prior MI19.4%8.7%15.4%17.3%16.7%17.9%
Comorbidities
 COPD14.6%13.0%6.7%10.1%7.1%12.1%
 CVA6.8%8.7%3.9%10.1%3.5%7.7%
 Diabetes 32.0%17.4%29.3%25.7%24.8%28.6%
 Heart failure 38.8%56.5%29.4%49.2%20.1%42.9%
 Hypercoagulability 1.0%4.3%0.0%1.1%0.1%0.7%
 Hyperlipidemia 64.1%56.5%64.7%57.5%65.6%60.1%
 Hypertension66.0%52.2%65.9%59.8%65.6%65.2%
 Major bleeding or ICH5.8%0.0%2.7%2.8%1.8%3.7%
 Renal failure17.5%13.0%7.9%10.6%5.8%8.4%
 Valve disease14.6%30.4%8.2%19.6%7.9%16.1%
 VTE7.8%43.5%5.1%30.7%3.9%25.3%
AF
 No AF71.8%26.1%78.8%37.4%88.6%49.1%
 Prior but not current12.6%17.4%3.9%5.6%3.7%7.0%
 Prior and current6.8%30.4%3.0%22.4%2.8%23.1%
 New onset8.7%26.1%14.3%34.6%4.9%20.9%
Charlson Comorbidity Index (mean ± std)7.6 ± 4.538.1 ± 4.046.4 ± 3.938.2 ± 3.865.7 ± 3.767.6 ± 3.87
Mechanical value0.0%0.0%0.1%1.7%0.2%0.4%
Presentation
 Unstable angina70.9%56.5%49.1%35.2%39.8%27.1%
 STEMI3.9%0.0%6.0%8.9%14.9%22.7%
 Non-STEMI25.2%43.5%44.9%55.9%45.3%50.2%
In-hospital procedures
 PCI without stent3.9%8.7%6.1%7.8%5.1%6.2%
 PCI with bare metal stent1.9%0.0%1.3%1.7%27.4%37.0%
 PCI with drug eluting stent1.0%4.3%2.7%2.8%61.5%50.2%
 CABG2.9%13.0%45.7%32.4%1.3%0.7%
Number of vessels with CAD
 None30.1%43.5%18.8%29.1%3.9%7.0%
 Single15.5%13.0%14.8%22.3%44.1%35.2%
 Multiple54.4%43.5%66.4%48.6%52.0%57.9%
Hospital length of stay (mean ± std)9.2 ± 8.3211.1 ± 11.117.2 ± 6.9311.4 ± 11.193.0 ± 3.506.1 ± 8.62
Hospital discharged home81.6%69.6%83.4%68.7%94.6%83.5%

Note: AC: anticoagulant; CVD: cardiovascular disease; MI: myocardial infarction; COPD: chronic obstructive pulmonary disease; CVA: cerebral vascular accident; ICH: intracranial hemorrhage; VTE: vascular thrombus event; AF: atrial fibrillation; STEMI: ST elevated myocardial infarction; PCI: percutaneous coronary intervention; CABG: coronary artery bypass graph; CAD: coronary artery disease.