Myocardial Viability: From Proof of Concept to Clinical Practice

Table 1

Summary of studies evaluating improvement in segmental myocardial function with revascularisation.

Study	Period	Study design	Setting (center)	Patient ()	Modality of viability assessment	Sensitivity	Specificity
Arnese et al. [55]	1995	Prospective	Single	38	Stress TTE, PET	74, 89	95, 48
Cornel et al. [56]	1998	Prospective	Multi	61	Stress TTE	89	81
Pagano et al. [57]	1998	Prospective	Single	30	Stress TTE, PET	60, 99	33, 62
Bax et al. [58]	1999	Prospective	Single	68	Stress TTE	89	74
Pasquet et al. [59]	1999	Prospective	Single	94	Stress TTE, PET	69, 84	78, 37
Baer et al. [60]	2000	Prospective	Single	103	CMR, Stress TOE	86, 82	92, 83
Wiggers et al. [61]	2000	Prospective	Single	46	PET, Stress TTE	81, 51	56, 89
Cwajg et al. [29]	2000	Prospective	Single	45	PET, Stress TTE	91, 94	50, 48
Schmidt et al. [62]	2004	Prospective	Single	40	CMR, PET	96, 100	87, 73
Hanekom et al. [63]	2005	Prospective	Single	55	SRI, TTE	78, 73	77, 77
Slart et al. [64]	2006	Prospective	Single	47	DISA SPECT, PET	89, 90	86, 86

TTE, transthoracic echocardiography; TOE, transesophageal echocardiography; PET, photon emission tomography; CMR, cardiac magnetic resonance imaging; SRI, strain rate imaging echocardiography; DISA SPECT, dual-isotope simultaneous acquisition (DISA) SPECT.