Assessment of the Protective Role of Prenatal Zinc versus Insulin Supplementation on Fetal Cardiac Damage Induced by Maternal Diabetes in Rat Using Caspase-3 and KI67 Immunohistochemical Stains

Table 2

Pregnancy outcome and embryolethality in the different groups.

Parameter	Group								Chi-square	value
	C		STZ-DM		STZ-DM + Zn		STZ-DM + In
	No.	%	No.	%	No.	%	No.	%
Total rats	6	100	12	100	8	100	8	100	—	—
Mortality rate	0	0	6	50	2	25	2	25	66.67	<0.00001
Total number of corpora lutea (in metrial gland)	39		50		42		42		2.99	0.56
Resorptions	1	2.6	12	24	4	9.5	2	4.8	28.62	<0.00001
Total number of fetuses	38	97.4	38	76	38	90.5	40	95.2
Live fetuses	38	100	31	81.6	36	94.7	36	90	23.35	0.000034
Dead fetuses	0	0	7	18.4	2	5.3	4	10

C: control group, STZ-DM: streptozotocin-induced diabetic group, STZ-DM + In: streptozotocin-induced diabetic treated with insulin group, and STZ-DM + Zn: streptozotocin-induced diabetic treated with Zn group.
, compared to the control group and compared to the STZ-DM group.