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Cardiology Research and Practice
Volume 2017, Article ID 4751249, 8 pages
https://doi.org/10.1155/2017/4751249
Research Article

Divorce and Severity of Coronary Artery Disease: A Multicenter Study

1Section of Adult Cardiology, Cardiovascular Department, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia
2Cardiovascular Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia
3Cardiology Department, Zayed Military Hospital, Abu Dhabi, UAE
4Division of Cardiology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA, USA
5Cardiac Center, King Abdullah Medical City, Holy Capital, Makkah, Saudi Arabia
6Section of Pulmonology, Internal Medicine Department, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia
7Division of Gastroenterology and Hepatology, The Johns Hopkins Hospital, 1830 East Monument Street, Suite 428, Baltimore, MD 21287, USA
8Anesthesiology Department, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia
9Emergency Medicine Department, Cleveland Clinic Foundation, Cleveland, OH, USA
10Cardiology Unit, King Abdul Aziz University Hospital, Jeddah, Saudi Arabia
11Anesthesiology Department, King Abdul Aziz University Hospital, Jeddah, Saudi Arabia
12Suez Canal University, Ismailia, Egypt
13College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE
14Institute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE

Correspondence should be addressed to Amin Daoulah; moc.oohay@haluoadnima

Received 28 February 2017; Accepted 5 June 2017; Published 24 July 2017

Academic Editor: Stephan von Haehling

Copyright © 2017 Amin Daoulah et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The association between marital status and coronary artery disease (CAD) is supported by numerous epidemiological studies. While divorce may have an adverse effect on cardiac outcomes, the relationship between divorce and severe CAD is unclear. We conducted a multicenter, observational study of consecutive patients undergoing coronary angiography during the period between April 1, 2013, and March 30, 2014. Of 1,068 patients, 124 (12%) were divorced. Divorce was more frequent among women (27%) compared to men (6%). Most divorced patients had been divorced only once (49%), but a subset had been divorced 2 (38%) or ≥3 (12%) times. After adjusting for baseline differences, there was no significant association between divorce and severe CAD in men. In women, there was a significant adjusted association between divorce and severe MVD (OR 2.31 [1.16, 4.59]) or LMD (OR 5.91 [2.19, 15.99]). The modification of the association between divorce and severe CAD by gender was statistically significant for severe LMD ( 0.0008) and marginally significant for CAD ( 0.05). Among women, there was a significant adjusted association between number of divorces and severe CAD (OR 2.4 [95% CI 1.2, 4.5]), MVD (OR 2.0 [95% CI 1.4, 3.0]), and LMD (OR 3.4 [95% CI 1.9, 5.9]). In conclusion, divorce, particularly multiple divorces, is associated with severe CAD, MVD, and LMD in women but not in men.