Recurrent Stroke after Transcatheter PFO Closure in Cryptogenic Stroke or Tia: Long-Term Follow-Up

Table 3

Subgroup analysis of incidence of recurrent ischemic neurological events.

Risk score category	Recurrent stroke/TIA (n)	Recurrent stroke/TIA (%)	HR (95% CI)	value
RoPE 7–10	4	2.6	3.21	0.03
RoPE 0–6	20	8
CHA2DS2-Vasc 0–2	6	4	1.87	0.27
CHA2DS2-Vasc 3–7	18	7.2
HATCH 0–2	11	4.5	2.35	0.06
HATCH 3–4	13	9.9
ATRIA 0–8	6	3.8	2.02	0.19
ATRIA 9–15	18	7.4

Recurrent neurological events were more frequent in subjects with RoPE (Risk of Paradoxical Embolism) score < 7 than those with ≥ 7 (OR 3.21, ).