Clinical Study
Electrocardiogram Changes of Donepezil Administration in Elderly Patients with Ischemic Heart Disease
Table 2
Holter electrocardiogram and HRV at baseline and 4 weeks after donepezil intervention.
| | | Baseline | Donepezil | t | |
| | Mean HR (beats/min) | 74.5 ± 11.3 | 68.1 ± 10.4 | 3.2260 | 0.0013 | | The lowest HR (beats/min) | 53.2 ± 6.4 | 50.3 ± 6.8 | 2.4056 | 0.0177 | | Longest RR interval(s) | 1.36 ± 0.77 | 1.47 ± 0.84 | 0.7477 | 0.4561 | | LF (ms2) | 8.7 ± 8.5 | 8.9 ± 7.7 | 0.1351 | 0.8928 | | HF (ms2) | 4.6 ± 5.3 | 6.8 ± 4.6 | 2.4283 | 0.0152 | | LF/HF ratio | 2.14 ± 1.12 | 1.66 ± 1.08 | 2.3897 | 0.0169 |
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Note. Values are shown as mean ± SD. HR, heart rate; LF, low frequency; HF, high frequency.
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