Clinical Study

Elderly Patients with Moderate Chronic Ischemic Mitral Regurgitation: Coronary Artery Bypass Grafting Alone or Concomitant Mitral Annuloplasty?

Table 1

Baseline and procedure characteristics.

Unmatched populationMatched population
MAP groupCABG groupMAP groupCABG group
(n = 96)(n = 104)(n = 82)(n = 82)

Demographics
 Age (years)73.5 ± 2.274.4 ± 2.60.00973.8 ± 2.274.2 ± 2.50.278
 Gender (female)16 (16.7%)23 (22.1%)0.33114 (17.1%)17 (20.7%)0.720
 Obesity12 (12.5%)15 (14.4%)0.69110 (12.2%)12 (14.6%)0.832
 Smoking history38 (39.6%)39 (37.5%)0.76233 (40.2%)32 (39.0%)0.873

Concomitant diseases
 Hypertension64 (66.7%)65 (62.5%)0.53854 (65.9%)52 (63.4%)0.923
 Diabetes mellitus35 (36.5%)43 (41.3%)0.47931 (37.8%)34 (41.5%)0.804
 Hyperlipidemia23 (24.0%)29 (27.9%)0.52720 (24.4%)23 (28.0%)0.761
 COPD11 (11.5%)14 (13.5%)0.75710 (12.2%)11 (13.4%)0.815
 Prior CVA8 (8.3%)12 (11.5%)0.4507 (8.5%)9 (11.0%)0.804
 CKD9 (9.4%)12 (11.5%)0.6188 (9.8%)9 (11.0%)0.798

Preoperative cardiac status
 Previous PCI22 (22.9%)28 (26.9%)0.51319 (23.2%)21 (25.6%)0.875
 Recent MI43 (44.8%)37 (35.6%)0.18438 (46.3%)32 (39.0%)0.550
 NYHA III-IV27 (28.1%)21 (20.2%)0.18923 (28.0%)18 (22.0%)0.533
 LVEF0.43 ± 0.140.47 ± 0.130.0370.44 ± 0.150.46 ± 0.140.379
 LVEDD (mm)59.2 ± 6.656.8 ± 6.00.00858.7 ± 6.557.9 ± 6.10.418
 ERO (mm2)17 (13–18)15 (11–17)0.01617 (13–18)16 (12–17)0.158

Extent of CAD
 2-vessel14 (14.6%)13 (12.5%)0.66710 (12.2%)9 (11.0%)0.807
 3-vessel82 (85.4%)91 (87.5%)72 (87.8%)73 (89.0%)
 LM30 (31.3%)32 (30.8%)0.94126 (31.7%)27 (32.9%)0.867

Surgical data
 On-pump96 (100%)080 (100%)0
 CPB time (min)95.9 ± 21.4096.0 ± 21.40
 ACC time (min)78.5 ± 13.7079.5 ± 13.80
 Number of grafts3 (3, 3)3 (3, 3)0.5313 (3, 3)3 (3, 3)0.724
 Use of left IMA95 (99.0%)103 (99.0%)0.95581 (98.8%)82 (100%)0.316
 Use of right IMA05 (4.8%)0.03003 (3.7%)0.080
 Use of vein graft94 (97.9%)100 (96.2%)0.46581 (98.8%)80 (97.6%)0.560
 Use of RA3 (3.1%)5 (4.8%)0.7233 (3.7%)4 (4.9%)1.000

MAP group, patients undergoing combined CABG and mitral annuloplasty; CABG group, patients undergoing off-pump CABG alone. BMI, body mass index; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; CKD, chronic kidney disease; PCI, percutaneous coronary intervention; MI, myocardial infarction; AF, atrial fibrillation; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; LVD, left ventricular dysfunction; LVEDD, left ventricular endodiastolic diameter; LV, left ventricle; ERO, effective regurgitant orifice area; CAD, coronary artery disease; LM, left main trunk disease; CPB, cardiopulmonary bypass; ACC, aortic cross-clamping; IMA, internal mammary artery; RA, radial artery. Definition: obesity: body mass index of more than 30 kg/m2; recent MI: evidence of myocardial infarction within the last 30 days before surgery.