Effects of Cardiac Hypertrophy, Diabetes, Aging, and Pregnancy on the Cardioprotective Effects of Postconditioning in Male and Female Rats

Table 1

Effects of ischemia-reperfusion and PPC on heart contractility.

Treatment	+dP/dt		−dP/dt
	Ischemia	Reperfusion	Ischemia	Reperfusion
Ctr male	54.32 ± 3.48	58.89 ± 6.94	49.22 ± 2.09	48.28 ± 3.77
Ctr male + PPC	50.66 ± 3.55	80.45 ± 4.64	50.13 ± 3.83	80.22 ± 2.48
Ctr old male	55.30 ± 4.31	56.13 ± 4.53	56.32 ± 4.13	49.53 ± 3.94
Old male + PPC	49.78 ± 1.86	49.66 ± 2.88	58.86 ± 3.81	61.51 ± 4.33
Ctr female	54.59 ± 4.41	48.16 ± 6.70	52.45 ± 3.27	50.81 ± 3.99
Ctr female + PPC	50.66 ± 3.55	75.75 ± 3.43	50.13 ± 3.83	80.22 ± 2.48
Ctr old female	49.22 ± 2.09	48.28 ± 3.77	60.22 ± 4.14	59.91 ± 5.43
Ctr old female + PPC	56.08 ± 3.10	69.08 ± 4.75	56.62 ± 4.65	68.56 ± 2.77
Ctr male	59.31 ± 6.34	64.88 ± 4.99	54.54 ± 4.94	50.74 ± 3.07
Ctr male + PPC	50.66 ± 4.10	81.27 ± 3.02	52.57 ± 2.46	78.81 ± 3.66
Ctr LVH male	66.45 ± 5.47	76.57 ± 4.43	67.44 ± 2.43	76.99 ± 3.53
LVH male + PPC	69.32 ± 6.87	68.64 ± 2.78	68.74 ± 8.50	80.72 ± 5.22
Ctr female	53.82 ± 6.07	55.56 ± 6.25	54.77 ± 3.29	57.84 ± 5.05
Ctr female + PPC	62.63 ± 4.68	82.08 ± 2.96	61.76 ± 4.05	78.49 ± 4.64
Ctr LVH female	68.20 ± 7.11	72.83 ± 6.33	73.27 ± 9.72	71.35 ± 4.48
LVH female + PPC	56.99 ± 7.82	85.57 ± 7.14	52.61 ± 3.51	70.46 ± 6.42
Ctr diabetic male	59.31 ± 6.34	64.88 ± 4.99	54.54 ± 4.94	50.74 ± 3.07
Diabetic male + PPC	55.86 ± 4.02	59.29 ± 8.94	49.06 ± 2.68	47.53 ± 4.77
Ctr diabetic female	58.98 ± 5.09	55.04 ± 8.03	56.15 ± 3.46	58.39 ± 4.79
Diabetic female + PPC	53.05 ± 4.18	59.70 ± 8.90	47.84 ± 2.02	48.16 ± 4.68
Ctr female 19 GD	49.45 ± 2.59	63.63 ± 1.81	51.97 ± 1.24	65.17 ± 0.66
Female 19 GD + PPC	50.46 ± 3.36	72.59 ± 1.38	55.97 ± 1.57	71.27 ± 1.29
Ctr female 21 GD	47.19 ± 2.04	59.78 ± 1.46	47.84 ± 1.69	64.00 ± 0.43
Female 21 GD + PPC	49.79 ± 2.09	72.80 ± 1.88	50.95 ± 3.28	71.19 ± 0.63

Ctr: control; PPC: pacing postconditioning; LVH: left ventricle hypertrophy; GD: gestation day. compared to the respective control.