FibroAtlas: A Database for the Exploration of Fibrotic Diseases and Their Genes

Figure 1

(A) Three main types of queries are supported by the “Home” page: gene symbol query, nucleotide sequence query, and protein sequence query. Users can input the gene symbol such as “STAT3” in the query box. Users can also input a nucleotide or protein sequence, and the sequence similarity identity score from BLAST will be displayed. Choose the matched gene name and click “continue” to scan the set of search results. (B) In the result page, a table including the queried gene, related disease terminology, and supporting evidences is listed. (C) By clicking the gene symbol of “STAT3” in the “search results” interface, users can browse detailed information of “STAT3” and cross links to external databases. (D) By clicking the number of PubMed abstracts or sentences in the “search results” interface, users can scan a table containing the information of gene, associated disease terminology, PubMed ID, evidence, and manual curation. Click the link of evidence in this page to scan the abstract with highlighted keywords. (E) Three approaches for browsing are presented in the “Browse & Download” page. All the data can be downloaded.