Research Article

Cardiovascular Magnetic Resonance Imaging Evidence of Edema in Chronic Chagasic Cardiomyopathy

Table 1

Clinical characteristics of Chagas heart disease patients classified by groups.

Total Group 1FE > 60% Group 260% < FE > 35% Group 3FE < 35% value

Age (years)58.9 (SD 9.9)57.6 (SD 11.0)58.8 (SD 9.1)63.0 (SD 7.7)0.13
BMI26.2 (SD 4.3)26.7 (SD 3.9)26.0 (SD 4.3)25.6 (SD 5.7)0.38
Socioeconomic2.0 (SD 1.0)2.25 (SD 1.0)1.42 (SD 0.99)1.4 (SD 0.7)0.02
Female (%)53 (64.6)30 (81.0)18 (54.5)5 (41.7)0.013
Blood pressure (%)39 (47.6)18 (50.0)12 (40.0)9 (75.0)0.12
Type 2 diabetes (%)7 (8.9)4 (11.1)2 (6.7)1 (8.3)0.82
DLP (%)12 (15.4)8 (22.2)2 (6.7)2 (16.7)0.22
Smoking (%)3 (3.8)0 (0)2 (6.7)1 (8.33)0.25
NYHA1.5 (SD 0.5)1.4 (SD 0.5)1.4 (SD 0.6)1.7 (SD 0.4)0.19

CMR
LGE (%)48 (58.5)16 (43.2)21 (63.6)11 (91.7)0.01❖
FEVD54.2 (SD 9.8)58.6 (SD 5.5)55.0 (SD 6.8)38.2 (SD 11.6)0.01❖
LV telediastolic volume153.2 (SD 60.5)123.0 (SD 32.1)149.0 (SD 39.7)256 (SD 67.2)0.01❖⦿
LV telediastolic volume index87.1 (SD 34.7)70.9 (SD 16.9)82.5 (SD 24.7)150.6 (SD 29.8)0.01❖
LV telesystolic volume78.5 (SD 60.1)43.5 (SD 14.1)74.5 (SD 33.0)197.0 (SD 57.0)0.01❖⦿
LV telesystolic volume index44.2 (SD 35.8)24.3 (SD 7.6)41.0 (SD 20.1)114.0 (SD 26.5)0.01❖⦿
LV mass105.4 (SD 40.6)87.7 (SD 19.7)98.5 (SD 25.5)163.0 (SD 54.7)0.01❖
LV mass index57.9 (SD 21.3)49.2 (SD 13.4)53.0 (SD 15.3)89.7 (SD 20.0)0.01❖
VD telediastolic volume128.1 (SD 42.4)122.0 (SD 35.3)132.0 (SD 41.9)136.0 (SD 62.1)0.48
VD telediastolic volume index72.1 (SD 21.3)69.5 (SD 18.1)73.1 (SD 24.1)77.4 (SD 23.0)0.51
VD telesystolic volume58.9 (SD 29.2)49.8 (SD 16.1)60.2 (SD 27.0)83.9 (SD 48.4)0.01❖
VD telesystolic volume index33.9 (SD 15.1)28.5 (SD 8.3)34.8 (SD 16.0)48.2 (SD 19.5)0.01❖

LGE
Transmural (%)15 (31.2)3 (18.7)8 (38.1)4 (41.6)0.41
Subendocardic (%)27 (56.2)7 (43.7)10 (47.6)10 (90.9)0.03❖
Subepicardic (%)26 (54.2)7 (43.7)14 (66.7)5 (45.4)0.31
Midwall (%)41 (85.4)12 (75.0)20 (95.2)9 (81.8)0.21
Basal segments (%)35 (72.9)10 (62.5)18 (85.7)7 (63.6)0.21
Apical segments (%)21 (43.7)6 (37.5)7 (33.3)8 (72.7)0.08
Midcavity segments (%)18 (37.5)4 (25.0)7 (33.3)7 (63.7)0.11

Laboratory
Creatinine0.9 (SD 0.2)0.84 (SD 0.2)0.89 (SD 0.2)1.1 (SD 0.3)0.00❖
BUN17.6 (SD 7.9)16.2 (SD 5.6)18.5 (SD 8.3)19.4 (SD 11.6)0.34

Continuous variables are expressed as mean (SD, standard deviation). Categorical variables are expressed as the number of patients (%). BMI: body mass index; NYHA FC: New York Heart Association functional class. Post hoc comparisons between groups were not statistically significant otherwise indicated ⦿: significant difference between G2 and G1; : significant difference between G3 and G1; ❖: significant difference between G3 and G2. Obtained from http://www.pmod.com/files/download/v34/doc/pcardp/3615.htm.