Does Arterial Hypertension Affect Plasma Levels of Matrix Metalloproteinases and Their Tissue Inhibitors in Patients with Stable Coronary Artery Disease? A Preliminary Study

Table 5

Multiple regression analysis of the influence of independent variables such as HT, DM, and CAD stage on MMP-2, MMP-9, and TIMP-4 concentrations.

N = 70	Summary of dependent variable regression: MMP-2, R = 0.41825213, R^2 = 0.17493485; corrected R^2 = 0.13743188,  F (3.66) = 4.6646, ; error standard estimation: 47.404
	b	Standard error with b	b	Standard error with b	t (66)
W. free			137.9169	23.27753	5.924892	0.000001
HT	−0.021563	0.117932	−2.8099	15.36775	−0.182845	0.855480
DM	0.425553	0.118340	43.1472	11.99863	3.596006	0.000618
CCS II/CCS III	−0.011262	0.112410	−1.7938	17.90410	−0.100191	0.920496

CCSII/CCSIII: Canadian Cardiovascular Society classification of coronary artery disease clinical status; DM: diabetes; HT: hypertension; MMP-2: matrix metalloproteinase-2; W. free: word free. Statistical test used: ANOVA.