Research Article

MicroRNA-133b Alleviates Hypoxia Injury by Direct Targeting on NOD-Like Receptor Protein 3 in Rat H9c2 Cardiomyocyte

Figure 4

Regulated the cell damage of H9c2 by hypoxia in NLRP3-transfected or control cells. (a) Expression of NLRP3 mRNA. (b) Expression of NLRP3 protein (a: control; b: pEX; c: pEX-NLPR3). (c) Cell viability assay. (d) Cell migration assay. (e) Cell invasion assay. (f) Apoptosis assay. (g) Western blot detection of apoptotic proteins. (h) Quantification data. pEX: pEX-2 plasmids with empty vector; pEX-NLRP3: pEX-2 plasmids constructed NLRP3 vector. Error bars represent mean ± SD (n = 3). ; vs. control; vs. hypoxia.
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)