Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility

Table 5

Distribution of rs7895833 A > G, rs7069102 C > G, and rs2273773 C > T genotypes and alleles in patients with STEMI (ST-elevation myocardial infarction) and control subjects.

	Patients with STEMI		Control subjects		Statistical analysis
	(%)	(n)	(%)	(n)	χ^2
rs7895833 A > G genotype
AA	50.5	54	57.1	52	ns
AG	49.5	53	42.9	39	ns
GG	na
Allele
A	75	161	79	143	ns
G	25	53	21	39	ns
rs7069102 C > G genotype
CC	12	13	11	10
CG	66.7	72	50.5	46	7.2	0.027
GG	21.3	23	38.5	35	ns
Allele
C	45	98	36	66	3.4	0.066
G	55	118	64	116	ns
rs2273773 C > T genotype
CC	na
CT	100	107	100	91
TT	na
Allele
C
T

n, number of individuals; na, not available. Statistical evaluation by the chi-squared test. . STEMI, ST-elevation myocardial infarction.