Cardiology Research and Practice / 2019 / Article / Tab 6

Research Article

Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility

Table 6

Comparison of rs7895833 A > G, rs7069102 C > G, and rs2273773 C > T SNPs with SIRT1 and eNOS protein levels.

SIRT1 protein (ng/ml)eNOS protein (pg/ml)
STEMI groupControl groupSTEMI groupControl group

rs7895833 A > G genotype
 AA1.28 ± 1.10.71 ± 0.490.001274.23 ± 309.46503.17 ± 682.030.031
 AG1.22 ± 0.60.69 ± 0.430.002278.18 ± 323.81518.99 ± 384.520.002
 GGna
rs7069102 C > G genotype
 CC1.46 ± 0.660.70 ± 0.400.004262.40 ± 287.08416.91 ± 131.840.153
 CG1.21 ± 0.701.22 ± 0.440.002283.14 ± 350.69428.06 ± 304.500.024
 GG1.23 ± 0.720.72 ± 0.480.014255.11 ± 193.49626.22 ± 819.250.014
rs2273773 C > T genotypena
 CC
 CT
 TT

eNOS, endothelial nitric oxide synthase; SIRT1, sirtuin 1; STEMI, ST-elevation myocardial infarction. .

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