Cardiology Research and Practice / 2019 / Article / Tab 7

Research Article

Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility

Table 7

Values of the biochemical parameters in patients carrying the SIRT1 SNPs.

rs33 AArs 33AGrs102 CCrs 102CGrs102GG
STEMI ()CO ()STEMI ()CO ()STEMICOSTEMICOSTEMICO

Triglycerides (mg/dl)210.5 ± 119.37157.0 ± 110.440.021185.25 ± 108.68122.06 ± 148.210.032159.0 ± 112.58192.0 ± 261.980.680200.83 ± 119.97136.39 ± 103.740.005201.0 ± 95.13135.0 ± 96.280.016
LDL cholesterol (mg/dl)111.58 ± 51.85122.30 ± 35.470.228108.06 ± 38.90114.06 ± 36.760.473108.31 ± 33.22115.20 ± 41.480.662108.68 ± 40.54119.73 ± 36.240.154114.81 ± 65.55118.86 ± 35.240.765
HDL cholesterol (mg/dl)36.80 ± 9.3047.34 ± 12.07<0.00138.0 ± 10.2051.75 ± 15.95<0.00138.67 ± 9.7660.0 ± 20.920.01237.56 ± 9.6348.44 ± 13.59<0.00135.84 ± 10.2046.98 ± 10.53<0.001
VLDL (mg/dl)41.23 ± 24.4431.83 ± 22.030.04436.45 ± 21.7428.07 ± 36.310.18341.23 ± 24.4431.83 ± 22.030.35739.52 ± 24.3627.30 ± 20.780.00840.20 ± 19.0327.59 ± 19.260.021
TG/HDL6.35 ± 4.163.69 ± 3.220.0015.99 ± 6.202.69 ± 3.470.0024.70 ± 3.813.95 ± 6.130.3526.34 ± 5.733.29 ± 3.310.0016.34 ± 4.03.07 ± 2.240.003
Fasting blood glucose (mg/dl)128.82 ± 74.8474.38 ± 45.630.058144.26 ± 100.7892.97 ± 9.470.001132.08 ± 85.5085.50 ± 13.570.145138.50 ± 96.4096.61 ± 17.070.007133.03 ± 59.29107.46 ± 51.980.092
Uric acid (mg/dl)5.25 ± 1.184.45 ± 1.230.0035.38 ± 1.384.38 ± 1.300.0025.45 ± 1.054.63 ± 1.440.1485.35 ± 1.294.47 ± 1.260.0025.12 ± 1.444.31 ± 1.220.057
BMI28.65 ± 3.2725.0 ± 3.90<0.00128.82 ± 4.7724.33 ± 3.96<0.00129.23 ± 6.7124.32 ± 5.310.07128.72 ± 3.6925.15 ± 3.60<0.00128.3 ± 3.4824.25 ± 3.95<0.001

n, number of individuals. Statistical evaluation by Student’s t-test. The results are shown as mean ± standard deviation (SD). HDL, high-density lipoprotein; LDL, low-density lipoprotein; VLDL, very low-density lipoprotein; BMI, body mass index. .

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