Cardiology Research and Practice

Research Article

Myocardial Scar on Surface ECG: Selvester Score, but Not Fragmentation, Predicts Response to CRT

Table 2

Population baseline characteristics and distribution between responders and nonresponders.


Variables	All patients (n = 178, 100%)	Responders (n = 106, 59.5%)	Nonresponders(n = 72, 40.5%)	value

Age	70 ± 10	70.4 ± 10	70 ± 9	0.729
Males	120 (67.4%)	62 (58.5)%	58 (80.6%)	0.002
Females	58 (32.6%)	44 (41.5%)	14 (19.4%)	0.002
NYHA class II	32 (18.0%)	23 (21.7%)	9 (13.5%)	0.117
III	146 (82.0%)	83 (78.3%)	63 (87.5%)
Ischemic etiology	64 (35.9%)	36 (34.0%)	28 (38.9%)	0.457
QRS (ms)	161 ± 18	163 ± 18	158 ± 18	0.115
AF	20 (11.2%)	6 (5.7%)	14 (19.4%)	0.004
Hypertension	85 (47.7%)	67 (63.2%)	45 (62.5%)	0.996
DM	46 (25.8%)	21 (19.8%)	25 (34.7%)	0.022
Dyslipidemia	72 (40.4%)	41 (38.7%)	31 (43.1%)	0.776
ACE-is/ARBs	160 (89.9%)	97 (91.5%)	62 (86.1%)	0.367
Beta-blockers	142 (79.8%)	89 (84.0%)	53 (73.6%)	0.127
Statins	70 (39.3%)	39 (36.8%)	31 (43.1%)	0.360
MRAs	81 (45.5%)	50 (47.2%)	30 (41.7%)	0.519
Diuretics	148 (83.1%)	86 (81.1%)	61 (84.7%)	0.354
LVEF (%)	27.5 ± 5.6	26.8 ± 5.5	28.6 ± 5.5	0.037
LVEDV (mL)	192 (152–228)	193 (165–229)	177 (132–227)	0.156
LVESV (mL)	137 (110–170)	140 (116–175)	135 (94–165)	0.244
LVEDD (mm)	69.2 ± 10.2	68.3 ± 9.4	70.7 ± 11.3	0.238
LVESD (mm)	57.8 ± 11.3	57.4 ± 10.8	58.5 ± 12.3	0.638
Selvester score	7 (4–10)	5 (3–8)	8 (6–12)	<0.001
Selvester score ≥ 7		42 (39.6)	47 (65.3%)	0.001
Fragmented QRS	74 (41.6%)	42 (39.6%)	32 (44.4%)	0.457

Continuous variables are expressed as mean ± SD, and compared by the independent samples Student’s t-test, or as median and 25°/75° percentiles, and compared by the Mann–Whitney U test, as appropriate (); categorical variables as number of patients (%) and compared by the χ2 test. AF, atrial fibrillation; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; DM, diabetes mellitus; ACE-I, angiotensin converting enzyme-inhibitors; ARBs, angiotensin receptor blockers; MRAs, mineralocorticoid receptor antagonists; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVEDV, left ventricular end-diastolic volume; and LVESV, left ventricular end-systolic volume.