Review Article
The Association of New-Onset Atrial Fibrillation and Risk of Cancer: A Systematic Review and Meta-Analysis
Table 2
Patient characteristics of the five studies.
| | Study | Age (years) | Sex (M/F %) | Hypertension | Hyperlipidemia | Diabetes | Definition | Incident cases | Types of cancer | | NOAF | N-NOAF | NOAF | N-NOAF | NOAF | N-NOAF | NOAF | N-NOAF | NOAF | N-NOAF | NOAF | CA | NOAF | Sub-CA |
| | Conen 2016 [9] | 58.0 (52.0–64.0) | 53 (49–58) | Female | NA | 610 | 8550 | 501 | 9988 | 64 | 870 | ECG or med report | Pathology/cytology reports | 1467 | 147 | Colon/breast cancer | | Wassertheil 2017 [10] | 66.9 ± 7.1 | 63.2 ± 7.3 | Female | NA | 2011 | 25716 | 905 | 11612 | 325 | 3199 | ECG or self-report | Medical diagnosis during the follow-up | 4,376 | 198 | Colorectal/breast cancer | | Hung 2018 [11] | 74 ± 13.6 | NA | 53.6/46.4 | NA | 3477 | NA | 864 | NA | 2981 | NA | ICD-9 | ICD-9 | 5130 | 330 | Colon/breast/liver/lung cancer | | Saliba 2018 [12] | 63.6 ± 13.6 | 64.3 ± 13.6 | 23.6/76.4 | NA | 4164 | 4868 | 3196 | 3990 | 1820 | 2147 | ECG | Pathology/cytology reports | 890 | 352 | Colorectal/breast cancer | | Vinter 2018 [13] | 56.2 (52.7–60.4) | NA | 47.6/52.4 | NA | NA | NA | NA | NA | NA | NA | ICD-8/10 or med report | ICD-10 | 2776 | 533 | Prostate/lung/colorectal/breast cancer | | Hung 2019 [14] | 70.8 ± 13.1 | NA | 55.2/44.8 | NA | 227956 | NA | 83207 | NA | 94515 | NA | ICD-9 | ICD-9 | 332555 | 22911 | 10 kinds of specific cancers |
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NOAF, new-onset atrial fibrillation; N-NOAF, not new-onset atrial fibrillation; Sub-CA, subsequent cancer; NA, not applicable; ECG, electrocardiography; ICD, International Classification of Diseases; Med, medicine.
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