Reduced Albuminuria and Potassemia Indicate Early Renal Repair Processes after Resynchronization Therapy in Cardiorenal Syndrome Type 2

Table 2

Selected demographic and clinical data and test results in the study group prior to CRT implantation according to NYHA heart failure classes.

Variable	NYHA II (n = 27)	NYHA III and IV (n = 37)
Age, years	67.75 ± 6.07	69.17 ± 10.5	0.547
Female gender, n (%)	2 (8.33)	13 (33.33)	0.033
BMI (kg/m^2)	29.3 ± 5.48	28.8 ± 5.31	0.723
CAD, n (%)	18 (66.67)	29 (78.38)	0.071
T2DM, n (%)	15 (62.5)	16 (41.03)	0.097
HA, n (%)	21 (87.5)	28 (71.79)	0.214
sCr (mg/dL)	1.125 ± 0.35	1.19 ± 0.36	0.08
eGFR CKD-EPI (mL/min/1,73 m^2)	63.95 ± 19.15	63.04 ± 19.84	0.429
uNGAL (ng/mL)	16.63 ± 18.19	43.63 ± 60.02	0.041
uNCR (µg/g)	53.73 ± 177.0	75.49 ± 155.08	0.056
uAlb (mg/dL)	92.32 ± 164.94	81.87 ± 138.65	0.079
uACR (mg/g)	207.42 ± 573.85	116.76 ± 231.52	0.291
uCr (mg/dL)	130.46 ± 80.83	97.82 ± 63.47	0.304
HCT (%)	41.58 ± 4.03	39.89 ± 4.5	0.029
Hb (g/dL)	13.73 ± 1.36	13.17 ± 1.79	0.214
RBC, millions per K/µL	4.56 ± 0.42	4.50 ± 0.58	0.113
WBC, thousands per K/µL	7.30 ± 2.22	7.28 ± 2.72	0.025
PK, thousands per K/µL	197.5 ± 43.07	213.31 ± 69.97	0.114
Na (mmol/L)	137.08 ± 2.18	136.44 ± 3.44	0.085
K (mmol/L)	4.41 ± 0.31	4.38 ± 0.51	0.222

Abbreviations: BMI, body mass index; CAD, coronary artery disease; T2DM, type 2 diabetes; HA, hypertension; sCr, creatinine serum; eGFR CKD-EPI, estimated glomerular filtration rate calculated using Chronic Kidney Disease Epidemiology Collaboration; uNGAL, lipocalin associated with neutrophil gelatinase in a single sample of urine; uNCR, urinary NGAL to creatinine ratio; uAlb, urinary albumin concentration in a single morning sample of urine; uACR, urinary albumin to creatinine ratio; uCr, urea creatinine; HCT, hematocrit, Hb, hemoglobin; RBC, red blood cell count; WBC, white blood cell count; PK, platelet count; Na, sodium; K, potassium; CRP, C-reactive protein.