Research Article

Echocardiographic Predictors of All-Cause Mortality in Patients with Hypertrophic Cardiomyopathy following Pacemaker Implantation

Table 1

Baseline characteristics of enrolled patients according to LAD and LVEDD.

VariablesAll patients (n = 74)LAD ≥44 mm (n = 28)LAD <44 mm (n = 46) valueAll patients (n = 76)LVEDD ≥43 mm (n = 48)LVEDD <43 mm (n = 28) value

Female, n (%)39 (52.7)14 (50.0)25 (54.3)0.71639 (51.3)21 (43.8)18 (64.3)0.084
Age, yrs58.1 ± 14.960.8 ± 15.656.4 ± 14.40.22357.6 ± 15.257.4 ± 14.958.0 ± 15.90.865
HTN, n (%)21 (28.4)7 (25.0)14 (30.4)0.61521 (27.6)16 (33.3)5 (17.9)0.146
DM, n (%)11 (14.9)4 (14.3)7 (15.2)0.91311 (14.5)9 (18.8)2 (7.1)0.294
CHD, n (%)9 (12.2)4 (14.3)5 (10.9)0.6639 (11.8)7 (14.6)2 (7.1)0.548
AF, n (%)31 (41.9)16 (57.1)15 (32.6)0.03832 (42.1)22 (45.8)10 (35.7)0.389
AVB, n (%)17 (23.0)5 (17.9)12 (26.1)0.41418 (23.7)11 (22.9)7 (25.0)0.837
LVOTO, n (%)36 (48.6)10 (35.7)26 (56.5)0.08237 (48.7)20 (41.7)17 (60.7)0.109
IVST (mm)16.0 (13.0–21.0)16.0 (12.3–19.0)16.0 (14.0–21.0)0.34516.0 (13.0–21.0)16.0 (12.0–20.0)16.0 (14.0–24.0)0.274
LAD (mm)41.7 ± 7.841.7 ± 7.843.8 ± 8.438.3 ± 5.40.003
LVEDD (mm)45.4 ± 6.548.3 ± 6.543.7 ± 5.90.00345.7 ± 6.6
LVEF (%)63.1 ± 8.859.9 ± 10.565.0 ± 7.00.02763.0 ± 8.761.2 ± 8.966.1 ± 7.40.016
Pulmonary hypertension, n (%)5 (6.8)3 (10.7)2 (4.3)0.3606 (7.9)4 (8.3)2 (7.1)>0.999
Severe tricuspid regurgitation, n (%)6 (8.1)4 (14.3)2 (4.3)0.1916 (7.9)4 (8.3)2 (7.1)>0.999
SBP (mmHg)120.0 (110.0–131.25)120.0 (110.0–133.8)120.0 (107.5–131.3)0.866120.0 (110.0–130.0)120.0 (110.0–130.0)120.0 (102.5–137.5)0.732
DBP (mmHg)74.5 (64.8–80.0)70.0 (65.5–80.0)80.0 (64.8–80.0)0.45874.5 (65.8–80.0)70.0 (65.8–80.0)78.0 (65.5–80.0)0.455
HR (bpm)64.5 (57.8–72.0)64.5 (57.8–76.3)64.5 (57.8–71.3)0.79364.0 (57.3–71.8)63.5 (57.3–71.5)68.0 (57.8–71.8)0.351
Medications
Β-blocker, n (%)60 (81.1)23 (82.1)37 (80.4)0.85662 (81.6)36 (75.0)26 (92.9)0.053
CCB, n (%)35 (47.3)10 (35.7)25 (54.3)0.11936 (47.4)21 (43.8)15 (53.6)0.408
ACEI/ARB, n (%)22 (29.7)13 (46.4)9 (19.6)0.01422 (28.9)17 (35.4)5 (17.9)0.103
AMIO, n (%)10 (13.5)5 (17.9)5 (10.9)0.61610 (13.2)6 (12.5)4 (14.3)0.999
Warfarin, n (%)7 (9.5)4 (14.3)3 (6.5)0.2687 (9.2)6 (12.5)1 (3.6)0.250
Dual-chamber pacing, n (%)64 (86.5)21 (75.0)43 (93.5)0.05765 (85.5)39 (81.3)26 (92.9)0.294
RV apical pacing, n (%)73 (98.6)28 (100.0)45 (97.8)>0.99975 (98.7)48 (100.0)27 (96.4)0.368

Data are presented as mean ± SD, median (interquartiles), or n (%). LAD, left atrial diameter; LVEDD, left ventricular end-diastolic diameter; HTN, hypertension; DM, diabetes mellitus; CHD, coronary heart disease; AF, atrial fibrillation; AVB, atrioventricular block; LVOTO, left ventricular outflow tract obstruction; IVST, interventricular septum thickness; LVEF, left ventricular ejection fraction; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; CCB, calcium-channel blocker; ACEI/ARB, angiotensin-converting enzyme inhibitor/angiotensin-receptor blocker; AMIO, amiodarone; RV, right ventricular.