Research Article
The Association between Trimethylamine N-Oxide and Its Predecessors Choline, L-Carnitine, and Betaine with Coronary Artery Disease and Artery Stenosis
Table 1
Baseline characteristics of subjects stratified by CON and CAD.
| | | CON (n = 73) | CAD (n = 94) | |
| | Male (n, %) | 31 (42.47%) | 40 (42.55%) | 1 | | Age (years) | 56 ± 1 | 57 ± 1 | 0.59 | | Height (cm) | 160 ± 1 | 162 ± 1 | 0.12 | | Weight (kg) | 63 ± 2 | 66 ± 1 | 0.29 | | BMI (kg/m2) | 25 ± 1 | 25 ± 0 | 0.5 | | SBP (mmHg) | 128 ± 3 | 138 ± 3 | 0.01 | | DBP (mmHg) | 75 ± 2 | 81 ± 1 | 0.01 | | HR | 73 (66–85) | 71 (66–80) | 0.31 | | Glu (mmol/L) | 4.96 (4.57–5.73) | 5.46 (4.77–6.64) | 0.01 | | TCHO (mmol/L) | 4.49 ± 0.13 | 4.61 ± 0.12 | 0.71 | | TG (mmol/L) | 1.31 (0.97–1.85) | 1.85 (1.31–2.65) | <0.01 | | HDL (mmol/L) | 1.03 (0.88–1.25) | 0.96 (0.83–1.18) | 0.09 | | LDL (mmol/L) | 2.78 ± 0.09 | 2.83 ± 0.09 | 0.81 | | HGB (g/L) | 133.5 (122–141.75) | 135 (126.5–147) | 0.07 | | Cr (μmol/L) | 82.89 ± 2.30 | 86.54 ± 2.41 | 0.23 | | ALT (U/L) | 19.1 (15.1–29.48) | 21.1 (15.4–32.7) | 0.3 | | AST (U/L) | 22.93 (18.35–29.1) | 20.8 (18.05–31.5) | 0.92 | | TMAO (μM) | 1.18 (0.67–1.7) | 1.46 (0.8–2.32) | 0.03 | | Choline (μM) | 8.30 (6.90–10.14) | 8.37 (6.76–9.56) | 0.99 | | L-Carnitine (μM) | 43.08 (33.81–49.51) | 43.16 (35.44–48.94) | 0.96 | | Betaine (μM) | 37.84 (29.44–42.14) | 32.64 (26.11–41.33) | 0.08 |
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Continuous data are presented as mean ± SD or median (interquartile range), and categorical variables are presented as counts and percentage (%).
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