Association of c.56C > G (rs3135506) Apolipoprotein A5 Gene Polymorphism with Coronary Artery Disease in Moroccan Subjects: A Case-Control Study and an Updated Meta-Analysis
Table 3
Association between APOA5 variant genotypes and clinical and biochemical parameters.
Parameter
Genotypes
value
value
value
value
CC
CG
GG
(CC vs. CG)
(CC vs. GG)
(CC vs. CG + GG)
(CC + CG vs. GG)
(n = 210)
(n = 28)
(n = 18)
Dbp (mmgHg)
78.57 ± 9.78
79.18 ± 16.79
84.94 ± 8.73
0.779
0.008
0.102
0.016
Sbp (mmgHg)
123 [119–133]
127 [120–146]
147 [135–175]
0.285
<0.001
0.005
<0.001
BMI (kg/m2)
26.18 ± 4.22
25.66 ± 4.99
25.93 ± 5.84
0.550
0.821
0.568
0.866
LDL (mg/dl)
126 ± 39
121 ± 35
150 ± 50
0.531
0.064
0.327
0.057
HDL (mg/dl)
51 ± 16
50 ± 13
45 ± 16
0.667
0.131
0.218
0.132
TC (mg/dl)
194 ± 40
192 ± 37
230 ± 64
0.816
0.033
0.125
0.032
TG (mg/dl)
113 [75–151]
105 [76–133]
212 [158–273]
0.477
<0.001
0.021
<0.001
Gly (mg/dl)
98 [88–119]
92 [90–95]
115 [99–181]
0.281
0.018
0.557
0.012
Sbp: systolic blood pressure, Dbp: diastolic blood pressure, BMI: body mass index, TG: triglycerides, LDL: low-density lipoprotein cholesterol, HDL: high-density lipoprotein cholesterol, Gly: glycemia, TC: serum total cholesterol.
