Association of c.56C > G (rs3135506) Apolipoprotein A5 Gene Polymorphism with Coronary Artery Disease in Moroccan Subjects: A Case-Control Study and an Updated Meta-Analysis
Table 5
Association between c.56C > G variant and risk of CAD in the meta-analysis.
Model
Number of included studies
Test of association
Test of heterogeneity
Publication bias
OR
95% CI
value
Model
value
I2 (%)
value (Egger’s test)
Recessive model (CC + CG vs. GG)
10
3.39
[1.77–6.50]
<0.001
Random
0.05
50
0.086
Dominant model (CC vs. CG + GG)
10
1.35
[0.97–1.87]
0.07
Random
0.001
67
0.700
Co-dominant model (CC vs. CG)
10
1.17
[0.84–1.63]
0.35
Random
0.002
65
0.798
Co-dominant model (CC vs. GG)
10
3.96
[2.44–6.45]
<0.001
Fixed
0.31
15
0.914
Allele contrast (C vs. G)
12
1.29
[1–1.68]
0.05
Random
<0.001
80
0.117
Number of included studies includes our case control study data.