Research Article

Upregulation of MicroRNA-125b Leads to the Resistance to Inflammatory Injury in Endothelial Progenitor Cells

Figure 3

miR-125b overexpression enhanced the EPC-mediated neovascularization and cardiac function recovery in the ischemic hearts. The cardiac function was assessed by echocardiography at baseline and after MI (28 days). Representative (a) and quantification (b) of echocardiography analyses. EPC-mediated neovascularization in the ischemic hearts analyzed by CD31 staining (GFP) (c) and capillary density quantified (d) (scale bar = 100 μm, vs. NC mimic, n = 5).