Research Article
Aliskiren Improved the Endothelial Repair Capacity of Endothelial Progenitor Cells from Patients with Hypertension via the Tie2/PI3k/Akt/eNOS Signalling Pathway
Figure 1
The quantification analysis of the in vitro function and in vivo reendothelialization capacity of human EPCs in the two groups. (a) Quantification analysis of human EPC migration ( vs. EPCs from normotensive subjects, n = 18 per group). (b) Quantification analysis of the proliferative activity of human EPCs ( vs. EPCs from normotensive subjects, n = 18 per group). (c)–(d) Quantification analysis of human EPC adhesion to HUVECs with or without TNF-α activation ( vs. EPCs from normotensive subjects, n = 18 per group). (e) Quantification analysis of the area of carotid artery reendothelialization by transplanted EPCs on day 3 after injury ( vs. EPCs from normotensive subjects, n = 18 per group). hpf = high-power field.
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