Electrocardiographic Characteristics of Breast Cancer Patients Treated with Chemotherapy
Table 3
ECG changes before and at each follow-up point during chemotherapy in BC patients.
ECG changes
T0
T1
value
T2
value
T3
value
Abnormal ECG, n (%)
28 (43.75)
36 (56.25)
0.157
41 (64.06)
0.021
42 (65.63)
0.013
ST-T changes, n (%)
7 (10.94)
10 (15.63)
0.435
10 (15.62)
0.435
10 (15.62)
0.435
ST changes
6 (9.38)
7 (10.94)
0.770
7 (10.94)
0.770
7 (10.94)
0.770
T-wave changes
1 (1.56)
6 (9.38)
0.052
8 (12.50)
0.016
6 (9.38)
0.052
Arrhythmias, n (%)
13 (20.31)
11 (17.19)
0.651
13 (20.31)
1.000
14 (21.88)
0.828
Sinus tachyarrhythmia
1 (1.56)
3 (4.69)
0.310
5 (7.81)
0.094
6 (9.38)
0.052
Ventricular premature beats
2 (3.13)
2 (3.13)
1.000
2 (3.13)
1.000
3 (4.69)
0.310
First-degree AVB
3 (4.69)
2 (3.13)
0.648
1 (1.56)
0.310
1 (1.56)
0.310
Intraventricular block
1 (1.56)
1 (1.56)
1.000
1 (1.56)
1.000
1 (1.56)
1.000
QTc prolongation, n (%)
3 (4.69)
4 (6.25)
0.697
1 (1.56)
0.310
2 (3.13)
0.648
fQRS, n (%)
17 (26.56)
27 (42.19)
0.063
30 (46.88)
0.017
34 (53.13)
<0.01
Values are mean ± SD. Compared with T0, . T0, baseline before chemotherapy; T1, after 1 cycle of chemotherapy; T2, after 3 cycles of chemotherapy; T3, end of chemotherapy; AVB, atrioventricular block; QTc, corrected QT interval; fQRS, fragmented QRS.