Electrocardiographic Characteristics of Breast Cancer Patients Treated with Chemotherapy

Table 4

Electrocardiographic parameters before and at each follow-up point during chemotherapy in BC patients.

Variables	T0	T1	value	T2	value	T3	value
HR (bpm)	76.66 ± 11.99	78.83 ± 11.30	0.321	81.23 ± 13.28	0.037	82.14 ± 12.74	0.013
PWA (mV)	0.11 ± 0.03	0.12 ± 0.03	0.454	0.12 ± 0.04	0.623	0.12 ± 0.04	0.438
PWD (ms)	95.53 ± 12.05	95.61 ± 11.60	0.973	94.06 ± 11.87	0.529	96.19 ± 16.58	0.779
PRI (ms)	148.97 ± 20.37	148.05 ± 21.29	0.835	147.78 ± 21.54	0.788	149.58 ± 34.16	0.890
Pd (ms)	20.38 ± 9.76	18.38 ± 9.66	0.218	18.31 ± 8.75	0.204	16.81 ± 9.41	0.029
QRS axis (°)	39.33 ± 30.13	37.83 ± 30.28	0.769	40.29 ± 24.74	0.853	37.49 ± 29.51	0.720
QRSD (ms)	87.05 ± 13.88	87.02 ± 12.88	0.989	89.14 ± 12.66	0.371	91.64 ± 13.43	0.050
QTc (ms)	411.38 ± 26.83	415.61 ± 26.67	0.378	414.94 ± 32.45	0.458	421.69 ± 21.30	0.032
QTd (ms)	21.25 ± 10.95	24.75 ± 11.92	0.102	27.50 ± 13.50	<0.01	24.94 ± 11.71	0.085
TpTe (ms)	73.63 ± 14.20	76.31 ± 18.64	0.386	76.69 ± 21.64	0.323	80.13 ± 14.37	0.037
RR (s)	0.80 ± 0.12	0.78 ± 0.11	0.252	0.76 ± 0.12	0.042	0.75 ± 0.11	0.011
SV1 (mV)	1.18 ± 0.41	1.30 ± 0.41	0.144	1.42 ± 0.49	<0.01	1.49 ± 0.48	<0.01
RV5 (mV)	0.74 ± 0.33	0.79 ± 0.38	0.512	0.84 ± 0.42	0.158	0.88 ± 0.40	0.037
SLI (mV)	1.92 ± 0.59	2.08 ± 0.61	0.151	2.26 ± 0.69	<0.01	2.37 ± 0.65	<0.01
iCEB	4.29 ± 0.59	4.26 ± 0.54	0.781	4.10 ± 0.62	0.069	4.03 ± 0.53	0.011

Values are mean ± SD. Compared with T0, . T0, baseline before chemotherapy; T1, after 1 cycle of chemotherapy; T2, after 3 cycles of chemotherapy; T3, end of chemotherapy; HR, heart rate; PWA, P-wave amplitude; PWD, P-wave duration; PRI, PR interval; Pd, P-wave dispersion; QRSD, QRS duration; QTc, corrected QT interval; QTd, QRS dispersion; TpTe, T-peak to T-end; SLI, Sokolow–Lyon index; iCEB: index of cardioelectrophysiological balance.