Research Article
Electrocardiographic Characteristics of Breast Cancer Patients Treated with Chemotherapy
Table 4
Electrocardiographic parameters before and at each follow-up point during chemotherapy in BC patients.
| Variables | T0 | T1 | value | T2 | value | T3 | value |
| HR (bpm) | 76.66 ± 11.99 | 78.83 ± 11.30 | 0.321 | 81.23 ± 13.28 | 0.037 | 82.14 ± 12.74 | 0.013 | PWA (mV) | 0.11 ± 0.03 | 0.12 ± 0.03 | 0.454 | 0.12 ± 0.04 | 0.623 | 0.12 ± 0.04 | 0.438 | PWD (ms) | 95.53 ± 12.05 | 95.61 ± 11.60 | 0.973 | 94.06 ± 11.87 | 0.529 | 96.19 ± 16.58 | 0.779 | PRI (ms) | 148.97 ± 20.37 | 148.05 ± 21.29 | 0.835 | 147.78 ± 21.54 | 0.788 | 149.58 ± 34.16 | 0.890 | Pd (ms) | 20.38 ± 9.76 | 18.38 ± 9.66 | 0.218 | 18.31 ± 8.75 | 0.204 | 16.81 ± 9.41 | 0.029 | QRS axis (°) | 39.33 ± 30.13 | 37.83 ± 30.28 | 0.769 | 40.29 ± 24.74 | 0.853 | 37.49 ± 29.51 | 0.720 | QRSD (ms) | 87.05 ± 13.88 | 87.02 ± 12.88 | 0.989 | 89.14 ± 12.66 | 0.371 | 91.64 ± 13.43 | 0.050 | QTc (ms) | 411.38 ± 26.83 | 415.61 ± 26.67 | 0.378 | 414.94 ± 32.45 | 0.458 | 421.69 ± 21.30 | 0.032 | QTd (ms) | 21.25 ± 10.95 | 24.75 ± 11.92 | 0.102 | 27.50 ± 13.50 | <0.01 | 24.94 ± 11.71 | 0.085 | TpTe (ms) | 73.63 ± 14.20 | 76.31 ± 18.64 | 0.386 | 76.69 ± 21.64 | 0.323 | 80.13 ± 14.37 | 0.037 | RR (s) | 0.80 ± 0.12 | 0.78 ± 0.11 | 0.252 | 0.76 ± 0.12 | 0.042 | 0.75 ± 0.11 | 0.011 | SV1 (mV) | 1.18 ± 0.41 | 1.30 ± 0.41 | 0.144 | 1.42 ± 0.49 | <0.01 | 1.49 ± 0.48 | <0.01 | RV5 (mV) | 0.74 ± 0.33 | 0.79 ± 0.38 | 0.512 | 0.84 ± 0.42 | 0.158 | 0.88 ± 0.40 | 0.037 | SLI (mV) | 1.92 ± 0.59 | 2.08 ± 0.61 | 0.151 | 2.26 ± 0.69 | <0.01 | 2.37 ± 0.65 | <0.01 | iCEB | 4.29 ± 0.59 | 4.26 ± 0.54 | 0.781 | 4.10 ± 0.62 | 0.069 | 4.03 ± 0.53 | 0.011 |
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Values are mean ± SD. Compared with T0, . T0, baseline before chemotherapy; T1, after 1 cycle of chemotherapy; T2, after 3 cycles of chemotherapy; T3, end of chemotherapy; HR, heart rate; PWA, P-wave amplitude; PWD, P-wave duration; PRI, PR interval; Pd, P-wave dispersion; QRSD, QRS duration; QTc, corrected QT interval; QTd, QRS dispersion; TpTe, T-peak to T-end; SLI, Sokolow–Lyon index; iCEB: index of cardioelectrophysiological balance. |