Research Article
Circulating Platelet-Derived Microparticles Associated with Postdischarge Major Adverse Cardiac Events in ST-Elevation Acute Myocardial Infarction
Table 3
Characteristics of subjects based on the PDMPs level measured in 30 days after discharge.
| | Characteristics | PDMPs increased (n = 45) | PDMPs decreased (n = 36) | value |
| | Gender (male), n (%) | 41 (91.1) | 34 (94.4) | 0.450 | | Age (years), mean ± SD | 54.6 ± 9.3 | 54.1 ± 8.9 | 0.795 | | Dyslipidemia, n (%) | 11 (24.4) | 11 (30.6) | 0.539 | | Diabetes mellitus, n (%) | 8 (17.8) | 10 (27.8) | 0.282 | | Ischemic heart disease, n (%) | 6 (13.3) | 10 (27.8) | 0.105 | | Hypertension, n (%) | 19 (42.2) | 17 (47.2) | 0.653 | | Current smoker, n (%) | 27 (60.0) | 23 (63.9) | 0.709 | | Onset (hours), median (Q1-Q3) | 6.0 ± 4.6 | 5.1 ± 3.7 | 0.365 | | Systolic BP (mmHg), mean ± SD | 129.8 ± 20.3 | 142.1 ± 29.4 | 0.028 | | Diastolic BP (mmHg), mean ± SD | 80.6 ± 11.9 | 87.5 ± 15.0 | 0.025 | | Heart rate (x/min), mean ± SD | 78.0 ± 16.2 | 80.4 ± 20.6 | 0.573 | | Anterior STEMI, n (%) | 23 (51.1) | 25 (69.4) | 0.095 | | Killip class ≥2 | 5 (11.1) | 6 (16.7) | 0.468 | | Revascularization | | | 0.689 | | Primary PCI | 24 (64.8) | 20 (62.5) | | | Fibrinolysis | 13 (48.1) | 12 (37.5) | | | Vessel disease | | | 0.208 | | 1 vessel disease | 11 (34.4) | 11 (52.4) | | | 2 vessel disease | 10 (31.3) | 6 (28.6) | | | 3 vessel disease | 10 (31.3) | 2 (9.5) | | | Any + left main disease | 1 (3.1) | 2 (9.5) | | | Culprit vessel | | | 0.296 | | Left anterior descendent | 19 (59.4) | 16 (76.2) | | | Right coronary artery | 11 (34.4) | 12 (23.8) | | | Left circumflexus | 2 (6.3) | 0 (0) | | | Intervention | | | 0.303 | | Drug-eluting stent | 31 (96.9) | 19 (90.5) | | | Bare metal stent | 1 (3.1) | 2 (9.5) | | | Haemoglobin (g/dL) | 14.2 ± 1.7 | 13.6 ± 1.6 | 0.084 | | Leucocytes (×103/mm3) | 12.8 ± 3.2 | 13.9 ± 3.8 | 0.150 | | Platelets (×103/mm3) | 269.9 ± 94.6 | 260.9 ± 57.9 | 0.620 | | Creatinine (mg/dL) | 1.1 ± 0.4 | 1.3 ± 0.5 | 0.019 | | Urea nitrogen (mg/dL) | 13.8 ± 4.4 | 16.8 ± 7.7 | 0.040 | | Random glucose (mg/dL) | 170.0 ± 81.3 | 162.4 ± 62.9 | 0.653 | | Clopidogrel | 45 (100) | 36 (100) | NA | | Acetylsalicylic acid | 45 (100) | 36 (100) | NA | | ACEI/ARB | 28 (62.2) | 26 (72.2) | 0.343 | | Beta blockers | 28 (62.2) | 23 (63.9) | 0.877 | | Furosemide | 8 (17.8) | 6 (16.7) | 0.895 | | Heparin | 32 (71.1) | 21 (58.3) | 0.230 |
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n = 69, n = 53. BP: blood pressure; STEMI: ST-elevation myocardial infarction; ACEI: angiotensin-converting enzyme inhibitors; ARB: angiotensin-receptor blocker; PDMPs: platelet-derived microparticles; NA: not applicable. |
