Impaired Mitophagy: A New Potential Mechanism of Human Chronic Atrial Fibrillation

Figure 3

Defective mitophagy in atrial myocytes of patients with chronic AF. (a) Representative immunofluorescence images and semiquantitative analysis of Cox IV in RAA (n = 9 per group, scale bar = 20 μm). (b) Representative western blots and quantification of protein expressions of Cox II and Cox IV in RAA (the SR group, n = 14; the AF group, n = 18).  < 0.05,  < 0.01 vs the SR group. SR, sinus rhythm; AF, atrial fibrillation; RAA, right atrial appendage.

(a)

(b)