Vitamin D (1,25-(OH)₂D₃) Improves Endothelial Progenitor Cells Function via Enhanced NO Secretion in Systemic Lupus Erythematosus

Figure 5

Correlation between the NO level in vitro and the number and activity of circulating EPCs. The linear regression relationship between the NO level in vitro and promoted circulating EPCs in response to 1,25-(OH)₂D₃. There was a significant linear regression relationship between the NO secretion level and the number of cultured EPCs (a). There was a significant linear regression relationship between the NO secretion level and the migratory and proliferative activities of EPCs (b), (c).

(a)

(b)

(c)