Effects of N-Acetylcysteine and N-Acetylcysteine Amide on Erythrocyte Deformability and Oxidative Stress in a Rat Model of Lower Extremity Ischemia-Reperfusion Injury

Table 2

Distribution of TAS, TOS, and OSI variables in groups.

	Sham (1) (mean ± Sd) (median ± IQR) n = 5	Ischemia (2) (mean ± Sd) (median ± IQR) n = 6	NAC (3) (mean ± Sd) (median ± IQR) n = 5	NACA (4) (mean ± Sd) (median ± IQR) n = 6	Test statistics values	Source of the difference
TAS	1.760 ± 0.027 (1.726–1.794)	1.498 ± 0.093 (1.414–1.742)	1.802 ± 0.166 (1.403–2.081)	1.800 ± 0.101 (1.640–1.925)	χ2(3) = 12.956; η2 = 0.553	1 > 2 (); 1 < 3 (); 1 < 4 (); 2 > 3 (); 2 > 4 (); 3 > 4 ()
TOS	17.140 ± 0.984 (15.584–19.495)	22.425 ± 2.055 (20.267–24.582)	18.532 ± 0.652 (17.704–19.759)	17.225 ± 0.842 (16.341–18.108)	χ2(3) = 15.756; η2 = 0.708	1 < 2 (); 1 < 3 (); 1 < 4 (); 2 > 3 (); 2 > 4 (); 3 > 4 ()
OSI	0.973 ± 0.047 (0.896–1.095)	1.498 ± 0.122 (1.289–1.564)	1.033 ± 0.075 (0.916–1.269)	0.960 ± 0.086 (0.863–1.079)	F(3.18) = 48.112∗∗; η2 = 0.889	1 < 2 (); 1 < 3 (); 1 > 4 (); 2 > 3 (); 2 > 4 (); 3 > 4 ()

F test statistics value. Kruskal–Wallis test statistics value. Statistical significance at the level of 0.05 (). Bonferroni correction used as a post hoc test. The Bonferroni-corrected Mann–Whitney U-test used as a post hoc test. Eta-square (partial-η²) effect size index for Kruskal–Wallis. Partial-eta-square (partial-η2) effect size index for ANOVA.