Clinical Study

Plasma Choline as a Diagnostic Biomarker in Slow Coronary Flow

Table 1

Clinical characteristic of the study subject.

NCF group (n = 21)SCF group (n = 44) value

Clinical and hemodynamic data
Age (years)58 ± 1056 ± 80.448
Male, n (%)4 (19)21 (47.7)0.026
BMI (kg/m2)24.03 ± 1.8624.24 ± 3.090.785
Smoking, n (%)4 (19)17 (38.6)0.114
Drinking, n (%)2 (9.5)15 (34.1)0.035
SBP (mmHg)128 ± 20127 ± 160.883
DBP (mmHg)75 ± 977 ± 100.425
HR (bpm)70 ± 1271 ± 110.650
Hypertension, n (%)10 (47.6)18 (40.9)0.609
DM, n (%)4 (19)3 (6.8)0.137
Hyperlipidemia, n (%)3 (14.4)14 (31.8)0.133

Baseline medication
ARB/ACEI, n (%)10 (47.6)24 (54.5)0.601
BB, n (%)11 (52.4)32 (72.7)0.105
CCB, n (%)7 (33.3)16 (36.4)0.811
Nitrates, n (%)4 (19)12 (27.3)0.472
Statins, n (%)17 (81)38 (86.4)0.572
Antiplatelet agent, n (%)17 (81)40 (90.9)0.253
Anticoagulant, n (%)3 (14.3)11 (25)0.326

Biochemical and hematological data
WBC (109/L)5.38 ± 1.636.16 ± 1.220.035
TG (mmol/L)1.30 ± 0.621.68 ± 1.150.167
TC (mmol/L)4.22 ± 0.694.16 ± 0.970.151
HDL (mmol/L)1.43 ± 0.411.26 ± 0.260.087
LDL (mmol/L)2.40 ± 0.652..42 ± 0.800.900
FPG (mmol/L)5.41 ± 0.805.16 ± 0.840.261
Creatinine (mmol/L)83.38 ± 30.1979.94 ± 13.040.521
Hs-CRP (mg/L)2.26 ± 2.302.30 ± 3.200.956

Data were expressed as mean ± standard error of the mean (SEM) or the number (%) of patients. NCF, normal coronary flow; SCF, slow coronary flow; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; DM, diabetes mellitus; ARB, angiotensin receptor blocker; ACEI, angiotensin converting enzyme inhibitor; BB, beta-blocker; CCB, calcium channel blocker; WBC, white blood cell; TG, triglyceride; TC, total cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FPG, fasting plasma glucose; Hs-CRP, high-sensitivity C-reactive protein;