Research Article

Association between Alanine Aminotransferase/Aspartate Aminotransferase Ratio (AST/ALT Ratio) and Coronary Artery Injury in Children with Kawasaki Disease

Table 1

Demographic characteristics.

Low-AAR groupHigh-AAR group value

Number12871290
Age (month)20.39 (11.85–35.77)20.45 (9.99–38.83)0.883
IVIG treat time (days)6.00 (6.00–7.00)7.00 (6.00–8.00)<0.001
Sex0.034
 Male821 (63.79%)874 (67.75%)
 Female466 (36.21%)416 (32.25%)
KD type<0.001
 Typical KD1059 (82.28%)883 (68.45%)
 Atypical KD228 (17.72%)407 (31.55%)
Fever1280 (99.46%)1275 (98.84%)0.088
Rash1044 (81.12%)905 (70.16%)<0.001
Conjunctivitis1189 (92.39%)1041 (80.70%)<0.001
Oral changes1193 (92.70%)1179 (91.40%)0.222
Extremity changes972 (75.52%)900 (69.77%)0.001
Lymph635 (49.34%)657 (50.93%)0.419
IVIG treat
 No use43 (3.43%)156 (12.29%)
 2 g/kgday1036 (82.62%)974 (76.75%)<0.001
 1 g/kgday175 (13.96%)139 (10.95%)
Steroid80 (6.24%)60 (4.66%)0.079

Results are given as (N) mean (SD) median (Q1–Q3)/N (%). KD: Kawasaki disease; AAR: aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio; IVIG: intravenous immunoglobulin therapy.