Association between Alanine Aminotransferase/Aspartate Aminotransferase Ratio (AST/ALT Ratio) and Coronary Artery Injury in Children with Kawasaki Disease
Table 2
Laboratory tests.
Low-AAR group
High-AAR group
value
Number (n)
1287
1290
White blood cell count (109/L)
15.83 (12.40–19.96)
14.80 (11.30–19.01)
<0.001
Hemoglobin (g/L)
110.16 (11.04)
110.70 (11.71)
0.227
Haematocrit (%)
0.33 (0.03)
0.33 (0.03)
0.170
Platelet count (109/L)
358.00 (289.00–439.00)
373.00 (300.50–473.00)
<0.001
Neutrophil count (109/L)
10.50 (7.74–14.21)
8.97 (6.25–12.30)
<0.001
Lymphocyte count (109/L)
3.43 (2.24–4.89)
3.63 (2.44–5.28)
0.002
Eosinophil count (109/L)
0.30 (0.12–0.57)
0.27 (0.10–0.55)
0.068
C-reactive protein (CRP, mg/L)
84.90 (49.89–132.00)
60.45 (27.95–101.25)
<0.001
Erythrocyte sedimentation rate (ESR, mm/h)
36.00 (27.00–45.00)
34.00 (24.00–43.00)
<0.001
Sodium (Na, mmol/L)
135.39 (2.66)
136.13 (2.55)
<0.001
Potassium (K, mmol/L)
4.25 (0.58)
4.41 (0.54)
<0.001
Chloride (Cl, mmol/L)
101.61 (3.34)
102.23 (3.06)
<0.001
Calcium (Ca, mmol/L)
2.27 (0.13)
2.33 (0.14)
<0.001
Magnesium (Mg, mmol/L)
0.91 (0.10)
0.93 (0.10)
<0.001
Phosphate (P, mmol/L)
1.37 (0.27)
1.48 (0.27)
<0.001
Alanine aminotransferase (ALT, μ/L)
73.00 (39.00–148.50)
17.00 (13.00–24.00)
<0.001
Aspartate aminotransferase (AST, μ/L)
34.00 (25.00–60.00)
30.00 (24.00–40.00)
<0.001
Albumin (g/L)
34.51 (6.42)
37.21 (6.24)
<0.001
Gamma-glutamyltransferase (γ-GT, μ/L)
89.00 (43.00–166.00)
16.00 (11.00–28.00)
<0.001
Total bilirubin (umol/L)
8.00 (5.20–13.20)
6.10 (3.90–8.90)
<0.001
Prothrombin time (PT, s)
13.99 (1.26)
13.64 (0.97)
<0.001
Activated partial thromboplastin time (APTT, s)
43.25 (6.61)
43.43 (6.27)
0.260
Fibrinogen (FIB, g/L)
6.39 (1.49)
5.80 (1.47)
<0.001
Thrombin time (s)
14.82 (1.01)
15.01 (1.29)
<0.001
D-dimers (μg/ml)
1.56 (0.94–2.48)
1.20 (0.71–1.88)
<0.001
N-terminal prohormone of brain natriuretic peptide (NT-pro BNP, pg/ml)
1082.00 (464.50–2687.50)
452.50 (198.75–1052.50)
<0.001
Immunoglobulin G (IgG, mg/L)
694.00 (562.75–865.00)
759.00 (572.00–948.00)
<0.001
Immunoglobulin A (IgA, mg/L)
61.80 (42.18–96.53)
68.60 (42.10–111.75)
0.099
Immunoglobulin M (IgM, mg/L)
114.50 (84.57–151.00)
117.50 (82.40–156.00)
0.883
Urinary white cell (>5/HP)
373 (44.19%)
270 (30.54%)
<0.001
Urinary protein
350 (41.32%)
256 (28.89%)
<0.001
Urinary red cell (>3/HP)
90 (11.24%)
72 (8.52%)
0.065
Results are given as (N) Mean (SD) Median (Q1–Q3)/N (%).
