Association between Alanine Aminotransferase/Aspartate Aminotransferase Ratio (AST/ALT Ratio) and Coronary Artery Injury in Children with Kawasaki Disease
Table 4
Multiple regression analysis.
Nonadjusted
Adjusted
IVIG resistance
Low-AAR group
1.0
1.0
High-AAR group
1.542 (1.279, 1.858) <0.0001
1.452 (1.036, 2.034) 0.0304
CAL (2 weeks)
Low-AAR group
1.0
1.0
High-AAR group
1.507 (1.253, 1.812) <0.0001
1.956 (1.265, 3.024) 0.0025
CAL (3–4 weeks)
Low-AAR group
1.0
1.0
High-AAR group
1.464 (1.168, 1.836) 0.0010
1.753 (1.125, 2.731) 0.0131
CAA (2 weeks)
Low-AAR group
1.0
1.0
High-AAR group
2.120 (1.253, 3.588) 0.0051
2.751 (1.405, 5.386) 0.0032
CAA (3–4 weeks)
Low-AAR group
1.0
1.0
High-AAR group
2.545 (1.360, 4.763) 0.0035
4.968 (1.061, 23.257) 0.0418
Statistic: β (95% CI) value/OR (95% CI). IVIG resistance; CAL: coronary artery lesions; CAA: coronary artery aneurysm. Adjust model for age and gender; IVIG treatment options; IVIG treatment time; value of AST; value of ALT; platelet count; neutrophil count; lymphocyte count; NT-pro BNP; immunoglobulin G; white blood cell count; C-reactive protein; albumin level.
