Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure
Table 2
Comparison between subgroups for basic clinical characteristics.
Subgroup A anaemic, LVEF < 40% n = 30
Subgroup B nonanaemic, LVEF < 40% n = 29
Subgroup C anaemic, LVEF ≥ 40% n = 22
Subgroup D nonanaemic, LVEF ≥ 40% n = 16
Anamnesis and physical examination
Age (years)
73.3 ± 9.8
62.7 ± 14.2
77.7 ± 8.3
75.3 ± 11.1
0.00003
B vs A#
B vs C#
B vs D#
Men
26 (86.7)
24 (82.8)
18 (81.8)
9 (47.5)
0.001
NYHA class: III/IV
15 (50.0)/15 (50.0)
22 (75.9)/7 (24.1)
14 (63.6)/8 (36.4)
11 (57.9)/5 (42.1)
0.469
Atrial fibrillation
18 (60.0)
11 (37.9)
16 (72.7)
6 (37.5)
0.042
Arterial hypertension
15 (50.0)
19 (65.5)
16 (72.2)
14 (87.5)
0.067
Chronic obstructive pulmonary disease
5 (16.7)
5 (17.2)
3 (12.6)
2 (12.5)
0.966
Chronic kidney disease
13 (44.8)
3 (10.3)
9 (40.9)
3 (18.8)
0.013
Diabetes mellitus
15 (50.0)
14 (48.3)
16 (72.2)
3 (18.8)
0.013
Laboratory tests
Creatinine (mg/dl)
1.50 ± 0.50
1.21 ± 0.44
1.40 ± 0.66
1.03 ± 0.24
0.012
A vs D
eGFR (ml/min/1.72 m2)
54.4 ± 23.1
69.2 ± 23.3
59.8 ± 25.4
68.6 ± 18.1
0.034
Urea (mg/dl)
59.6 ± 24.7
51.9 ± 33.7
58.7 ± 24.6
41.9 ± 11.3
0.137
hsTnT (ng/L)
134.0 ± 269.3
114.4 ± 319.5
54.8 ± 64.4
111.3 ± 317.2
0.767
NT-proBNP (pg/ml)
10105 ± 8825
5806 ± 7613
3666 ± 3083
3159 ± 3033
0.003
A vs B0.075
A vs C
A vs D
Haemoglobin (g/dl)
11.6 ± 1.3
14.7 ± 1.3
10.3 ± 1.7
13.7 ± 1.8
<0.000001
Haematocrit (%)
35.4 ± 3.4
44.3 ± 3.7
32.5 ± 3.4
41.7 ± 6.2
<0.000001
Iron (μg/L)
47.4 ± 20.9
67.0 ± 34.3
53.5 ± 25.7
62.9 ± 31.8
0.078
Transferrin saturation (%) data of 60 subjects
15.4 ± 7.1
20.8 ± 14.5
18.5 ± 11.5
20.2 ± 10.5
0.297
Data are presented as mean ± SD or n (%); ;;. eGFR, estimated glomerular filtration rate; NYHA, New York Heart Association; NT-proBNP, N-terminal probrain natriuretic peptide; hsTnT, high-sensitivity troponin T.
