Research Article
The Impact of Statins before High-Risk CABG on Postoperative Multiple Organ Function
| | PST (n = 503) | No PST (n = 377) | value |
| SOFA Maximum ≥11 | 24.3% (122/503) | 34.2% (129/377) | | SOFA maximum | 7.8 (3.0) | 9.2 (3.4) | | MACCE | 27.6% (139/503) | 35.0% (132/377) | | In-hospital mortality | 1.2% (6/503) | 1.1% (4/377) | | Nonfatal MI | 4.6% (23/503) | 4.8% (18/377) | | Nonfatal stroke | 0.6% (3/503) | 2.9% (11/377) | | New-onset AF | 18.1% (91/503) | 22.8% (86/377) | | New-onset VA | 6.6% (33/503) | 11.4% (43/377) | | Perioperative IABP | 13.3% (67/503) | 11.9% (45/377) | | Perioperative ECMO | 0.6% (3/503) | 0.0% (0/377) | | Reoperation | 3.6% (18/503) | 1.9% (7/377) | | After infection | 17.3% (87/503) | 9.0% (34/377) | | Pulmonary infection | 16.1% (81/503) | 9.0% (34/377) | | After bloodstream infection | 1.2% (6/503) | 0.0% (0/377) | | AKI | 5.4% (27/503) | 2.7% (10/377) | | CRRT | 2.8% (14/503) | 1.3% (5/377) | | Hepatic inadequacy | 17.7% (89/503) | 12.5% (47/377) | | Hypoxemia | 8.5% (43/503) | 6.1% (23/377) | | Noninvasive ventilator | 2.0% (10/503) | 8.0% (30/377) | | Reintubation | 2.2% (11/503) | 2.4% (9/377) | | Tracheotomy | 1.0% (5/503) | 0.0% (0/377) | | ICU stay (Day) | 2.7 (3.7) | 2.4 (1.8) | | Postoperative hospital stay (Day) | 8.1 (5.4) | 8.0 (3.0) | | Cost (RMB) | 138,636.1 (62,142.1) | 137,345.6 (36,636.8) | |
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MACCE: major adverse cardiovascular and cerebral events; MI: myocardial infarction; AF: previous atrial fibrillation; AKI: acute kidney injury; CRRT: continuous renal replacement therapy; IABP: intra-aortic balloon pump; ECMO: extracorporeal membrane oxygenation; SOFA : Sequential Organ Failure Assessment; VA: ventricular arrhythmias; PST: preoperative statin therapy.
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