Research Article
The Impact of Statins before High-Risk CABG on Postoperative Multiple Organ Function
Table 6
Independent risk factors for In-hospital hepatic inadequacy.
| | | In-hospital hepatic inadequacy | X2/t | value | Multivariate analysis OR (95% CI) | value | | YES (n = 136) | NO (n = 739) |
| | PST | 89 (65.4) | 414 (56.3) | 4.2 | 0.047 | 1.49 (1.01–2.18) | 0.042 | | Female gender | 35 (25.7) | 315 (42.6) | 13.7 | <0.0001 | 0.47 (0.31–0.72) | <0.0001 | | Euroscore II | 9.4 ± 5.4 | 9.0 ± 3.5 | 2.0 | 0.050 | | | | BMI | 24.2 ± 2.9 | 25.0 ± 3.1 | −2.5 | 0.357 | | | | Hypertension | 93 (68.4) | 365 (49.4) | 16.6 | <0.0001 | 2.18 (1.48–3.23) | <0.0001 | | Current smoker | 40 (29.4) | 200 (27.1) | 0.3 | 0.601 | | | | Previous MI | 25 (18.4) | 86 (11.6) | 4.7 | 0.035 | 1.72 (1.05–2.80) | 0.030 | | Previous TIA or CVA | 8 (5.9) | 46 (6.0) | 0.02 | 1.000 | | | | Previous PVD | 40 (29.4) | 151 (20.4) | 5.4 | 0.024 | 1.63 (1.08–2.46) | 0.020 | | Previous COPD | 34 (25.0) | 47 (6.9) | 47.5 | <0.0001 | 4.09 (2.47–6.78) | <0.0001 | | Ventricular aneurysm | 7 (5.1) | 71 (9.6) | 2.8 | 0.103 | | | | NYHA III and IV | 51 (37.5) | 264 (35.7) | 0.2 | 0.698 | | | | Emergency CABG | 5 (3.7) | 42 (5.7) | 0.9 | 0.413 | | | | Off pump | 51 (37.5) | 415 (56.2) | 16.1 | <0.0001 | 0.59 (0.40–0.87) | 0.008 | | Duration of operation (hours) | 4.5 ± 1.4 | 4.3 ± 1.0 | 1.8 | 0.079 | | |
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PST : Preoperative statin therapy; CABG: coronary artery bypass grafting; LVEF: left ventricular ejection fraction; BMI: body mass index; MI: myocardial infarction; TIA: prior transient ischemic attacks; CVA: cerebral vascular accident; PVD: previous peripheral vascular diseases; DM: diabetes mellitus COPD: previous chronic obstructive pulmonary diseases; NYHA : New York Heart Association.
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