Research Article
The Impact of Statins before High-Risk CABG on Postoperative Multiple Organ Function
Table 7
Independent risk factors for postoperative infection.
| | | Postoperative infection | X2/t | value | Multivariate analysis OR (95% CI) | value | | YES (n = 121) | NO (n = 759) |
| | PST | 87 (71.9) | 416 (54.8) | 12.5 | < 0.0001 | 2.09 (1.42–3.08) | <0.0001 | | Female gender | 42 (34.7) | 313 (41.2) | 1.8 | 0.195 | | | | Euroscore II | 8.4 ± 3.9 | 8.8 ± 3.8 | −1.1 | 0.275 | | | | BMI | 25.5 ± 3.3 | 24.8 ± 3.1 | 2.3 | 0.024 | 1.07 (1.01–1.14) | 0.024 | | Hypertension | 68 (56.2) | 395 (52.0) | 0.7 | 0.433 | | | | DM | 70 (57.9) | 301 (39.7) | 14.2 | <0.0001 | 1.76 (1.17–2.65) | 0.007 | | Previous MI | 26 (21.5) | 85 (11.2) | 10.0 | 0.003 | 1.73 (1.03–2.89) | 0.038 | | Previous TIA or CVA | 11 (9.1) | 43 (5.7) | 2.1 | 0.153 | | | | Previous PVD | 22 (18.2) | 169 (22.3) | 1.0 | 0.344 | | | | Hypercholesterolaemia | 43 (35.5) | 319 (42.0) | 1.8 | 0.196 | | | | Previous AF | 18 (14.9) | 112 (14.8) | 0.001 | 1.000 | | | | Previous COPD | 6 (5.0) | 80 (10.5) | 3.7 | 0.068 | | | | Ventricular aneurysm | 30 (24.8) | 48 (6.3) | 44.1 | <0.0001 | 4.44 (2.65–7.43) | <0.0001 | | Moderate and poor LVEF (<50%) | 72 (59.5) | 324 (42.3) | 11.6 | 0.001 | 1.82 (1.22–2.72) | 0.003 | | NYHA III and IV | 69 (57.0) | 256 (33.7) | 27.5 | <0.0001 | 2.60 (1.75–3.86) | <0.0001 | | Emergency CABG | 13 (10.7) | 34 (44.8) | 8.1 | 0.008 | 2.02 (1.01–4.04) | 0.047 | | Off pump | 63 (52.1) | 405 (53.4) | 0.07 | 0.845 | | | | Duration of operation (hours) | 4.2 ± 1.0 | 4.4 ± 1.1 | −1.1 | 0.305 | | |
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PST: preoperative statin therapy; CABG: coronary artery bypass grafting; LVEF: left ventricular ejection fraction; BMI: body mass index; MI: myocardial infarction; TIA: prior transient ischemic attacks; CVA: cerebral vascular accident; PVD: previous peripheral vascular diseases; DM: diabetes mellitus; NYHA : New York Heart Association.
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