Research Article

Heparin-Binding Protein: A Novel Biomarker Linking Four Different Cardiovascular Diseases

Table 2

Hub genes in the protein-protein interaction network.

RankAtherosclerosisMyocarditisMyocardial infarctionMyocardial ischemia

1IL10IL10F2IL10
2CXCL8IL4FGACXCL8
3IL4IFNGFGBPECAM1
4IFNGCXCL8GCPLG
5IL2IL2HRGAPOE
6IL3IL5APOBCXCL12
7CXCL12IL3FETUBIL4
8IL7CXCL12CPB2MPO
9PECAM1MPOF12IFNG
10IL5HMGB1ITIH3F2

The genes were ranked by scores with CytoHubba, and the top is considered to be the hub gene of the HBP in the disease.