Research Article
Functional Genetic Variant in ATG5 Gene Promoter in Acute Myocardial Infarction
Table 2
Genetic variants in ATG5 gene promoters in AMI patients and controls.
| | Genetic variants | Genotypes | Location1 | Controls (n = 386) | AMI (n = 378) | value |
| | g.106326740A > G | TC | −920 bp | 2 | 3 | 1.000 | | g.106326589G > A (rs506027) | GG | −769 bp | 83 | 78 | 0.883 | | | GA | | 177 | 180 | | | | AA | | 126 | 120 | | | g.106326584A > T | AT | −764 bp | 3 | 5 | 1.000 | | g.106326548G > T (rs117781908) | GT | −728 bp | 1 | 0 | — | | g.106326543G > T (rs182877945) | GT | −723 bp | 1 | 0 | — | | g.106326487G > A | GA | −667 bp | 1 | 2 | 1.000 | | g.106326427_28insA | -/A | −607 bp | 1 | 1 | 1.000 | | g.106326331G > A | GA | −511 bp | 1 | 2 | 1.000 | | g.106326293G > T (rs560549742) | GT | −473 bp | 1 | 0 | — | | g.106326168_70delTCT | TCT/- | −348 bp | 0 | 1 | — | | g.106326155T > C (rs510432) | TT | −335 bp | 83 | 78 | 0.883 | | | TC | | 177 | 180 | | | | CC | | 126 | 120 | | | g.106325913T > C | TC | −93 bp | 1 | 0 | — | | g.106325876C > T | CT | −56 bp | 1 | 1 | 1.000 | | g.106325849G > A | GA | −30 bp | 1 | 0 | — | | g.106325757C > G (rs190825454) | GG | +69 bp | 0 | 1 | — |
|
|
1Genetic variants are located upstream (-) to the transcription start site of the ATG5 gene at 106325820 of NC_000006.12.
|
