Impact of Platelet Glycoprotein Ia/IIa C807T Gene Polymorphisms on Coronary Artery Aneurysms of KD Patients

Table 4

Stratification analysis of platelet glycoprotein Ia/IIa C807T(rs1126643) gene polymorphism in Kawasaki disease cases and healthy controls.

Variable	rs1126643(cases/controls)		value^a	OR (95% CI)	value	Adjusted OR (95% CI)	Adjusted value^b
	CC/CT	TT
Age (months)
≤60	688/1167	41/109	0.0148	0.64 (0.44–0.93)	0.0177	0.64 (0.44–0.93)	0.0176
>60	83/111	6/14	0.2613	0.57 (0.21–1.56)	0.2744	0.57 (0.21–1.55)	0.2719
Gender
Male	516/853	36/78	0.1898	0.76 (0.51–1.15)	0.1957	0.76 (0.51–1.15)	0.1907
Female	255/425	11/45	0.0052	0.41 (0.21–0.80)	0.0094	0.40 (0.20–0.79)	0.0085
Coronary artery outcomes
NCAAs	660/1278	42/123	0.0216	0.66 (0.46–0.95)	0.0254	0.66 (0.46–0.95)	0.0242
CAAs	111/1278	5/123	0.0701	0.47 (0.19–1.17)	0.1039	0.46 (0.18–1.15)	0.0973

^a Two-sided χ² test for distributions between Kawasaki disease patients and healthy controls. ^bAdjusted for age and sex status in logistic regression models. NCAAs: noncoronary artery aneurysms; CAAs: coronary artery aneurysms; OR: odds ratio; CI: confidence interval; KD: Kawasaki disease.