Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina
Table 6
Distribution of genotype and allelic frequency and association analysis of -844G/A polymorphism with AMI under different genetic models.
Genotype/allele
Group I (AMI) (n = 100)
Group III (Control) (n = 100)
Odds ratio (95% CI)
value
GG
20 (20%)
24 (24%)
Ref
Ref
GA
56 (56%)
54 (54%)
1.24 (0.61–2.50)
0.541
AA
24 (24%)
22 (22%)
1.30 (0.57–2.99)
0.524
value—0.783
Recessive model
AA
24
22
1.11 (0.57–2.16)
0.736
GA + GG
76
78
Dominant model
GA + AA
80
76
1.26 (0.64–2.47)
0.495
GG
20
24
Codominant model
GA
56
54
1.08 (0.62–1.89)
0.776
GG + AA
44
46
Allele
G
96 (48%)
102 (51%)
1.12 (0.76–1.66)
0.548
A
104 (52%)
98 (49%)
OR: odds ratio, CI: confidence interval, and n: number in sample. Significant at .
