Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina
Table 7
Distribution of genotype and allelic frequency and association analysis of -844G/A polymorphism with CSA under different genetic models.
Genotype/allele
Group II (CSA) (n = 100)
Group III (control) (n = 100)
Odds ratio (95% CI)
value
GG
18 (18%)
24 (24%)
Ref
Ref
GA
54 (54%)
54 (54%)
1.33 (0.65–2.73)
0.432
AA
28 (28%)
22 (22%)
1.69 (0.74–3.88)
0.210
value 0.454
Recessive model
AA
28
22
1.37 (0.72–2.62)
0.328
GA + GG
72
78
Dominant model
GA + AA
82
76
1.43 (0.72–2.85)
0.298
GG
18
24
Codominant model
GA
54
54
1.00 (0.57–1.74)
1.000
GG + AA
46
46
Allele
G
90 (45%)
102 (51%)
1.27 (0.85–1.88)
0.230
A
110 (55%)
98 (49%)
OR: odds ratio, CI: confidence interval, and n: number in sample. Significant at .
