Early Dual-Antiplatelet Therapy at the Emergency Department Is Associated with Lower In-Hospital Major Adverse Cardiac Event Risk among Patients with Non-ST-Elevation Myocardial Infarction

Table 3

Univariate and multivariate analysis for in-hospital MACE rates.

Parameters	Univariate		Multivariate
	OR (95% CI)	value	OR (95% CI)	value
Demographics
Age	1.06 (1.03–1.08)	<0.001	1.05 (1.02–1.08)	<0.001
Sex
Female	Ref.	—	Ref.	—
Male	0.95 (0.48–1.87)	0.871	1.56 (0.71–3.45)	0.271
Time
<6 hours	Ref.	—	Ref.	—
>6 hours	2.51 (1.35–4.64)	0.003	2.09 (1.07–4.07)	0.030
Clinical diseases history
Smoking	0.73 (0.40–1.35)	0.317	0.88 (0.42–1.83)	0.731
Hypertension	1.83 (0.91–3.67)	0.087	—	—
Diabetes mellitus	1.05 (0.57–1.93)	0.868	0.71 (0.36–1.40)	0.322
CAD	0.96 (0.50–1.87)	0.914	—	—
CVA	2.67 (1.08–6.60)	0.034	1.64 (0.60–4.47)	0.332
CKD	1.02 (0.51–2.04)	0.966	0.68 (0.30–1.51)	0.342
Hyperlipidemia	0.84 (0.25–2.77)	0.768	—	—
Presentation features
Killip class
Level 1	Ref.		Ref.
Level 2–level 4	5.48 (2.95–10.19)	<0.001	5.16 (2.65–10.03)	<0.001
Heart rates	0.99 (0.98–1.01)	0.596	0.99 (0.98–1.00)	0.137
Peak troponin I	1.02 (1.01–1.04)	0.009	1.02 (1.01–1.04)	0.048
Angiographic finding
Left main disease	1.31 (0.50–3.40)	0.586	—	—
No. of disease vessels
1	3.52 (0.47–26.48)	0.150	—	—
2	2.18 (0.28–17.19)	0.959	—	—
3	3.16 (0.39–25.80)	0.355	—	—

CAD, coronary artery disease; CVA, cerebrovascular disease; CKD, chronic kidney disease.