Acute Hypobaric and Hypoxic Preconditioning Reduces Myocardial Ischemia-Reperfusion Injury in Rats

Table 1

Changes in mean blood pressure and heart rates.

Mean blood pressure (mmHg)	Baseline	15 min after ischemia	Reperfusion
			30 min	60 min
NN group	131.9 ± 12.1	104.1 ± 17.8	81.0 ± 13.8	74.8 ± 18.1
HH group	126.1 ± 18.6	97.1 ± 19.9	85.5 ± 20.8	87.8 ± 19.7
NH group	139.0 ± 20.4	105.0 ± 14.6	85.8 ± 9.6	76.5 ± 11.6
Hear rate (bpm)
NN group	275.6 ± 30.9	311.5 ± 40.6	278.5 ± 30.1	292.0 ± 43.5
HH group	269.5 ± 37.3	296.7 ± 43.7	288.4 ± 34.3	312.2 ± 41.8
NH group	298.1 ± 23.6	312.3 ± 30.2	283.2 ± 23.2	308.6 ± 45.5

Data are shown as mean ± standard deviation (SD). NN: normobaric normoxia; HH: hypobaric hypoxia; and NH: normobaric hypoxia.  < 0.05 vs. baseline in each group, n = 8, as assessed by using two-way ANOVA followed by Tukey’s post hoc test.