Research Article
Platelet Reactivity and Response to Aspirin and Clopidogrel in Patients with Platelet Count Disorders
Table 1
Patients’ characteristics.
| | Variable | Patients with thrombocytopenia (n = 64) | Patients with thrombocytosis (n = 30) | Controls (n = 80) | Statistical significance | | (1) | (2) | (3) |
| | Platelet count (G/L), mean ± SD (median, min-max) | 73 ± 34 (79, 11–139) | 683 ± 230 (567, 452–1136) | 211 ± 62 (195, 150–371) |
(1) vs. (2) vs. (3) | | ASA, n (%) | 64 (100) | 30 (100) | 80 (100) | NS | | Clopidogrel, n (%) | 15 (23) | 9 (30) | 31 (38) | NS | | Age, years (mean ± SD) | 68.2 ± 10.6 | 54.4 ± 24.6 | 61 ± 8.5 |
(1) vs. (2), (1) vs. (3) | | WBC (mean ± SD) | 6 ± 4.3 | 8.3 ± 2 | 7 ± 2.8 | NS | | RBC (mean ± SD) | 3.7 ± 0.8 | 4.2 ± 0.6 | 4.2 ± 0.7 |
(1) vs. (3) | | Hb (mean ± SD) | 10.7 ± 2.2 | 12.8 ± 2.0 | 12.7 ± 2.3 |
(1) vs. (2) (1) vs. (3) | | Arterial hypertension, n (%) | 21 (33) | 12 (40) | 37 (46) | NS | | Diabetes mellitus, n (%) | 11 (17) | 6 (20) | 20 (25) | NS | | Kidney insufficiency, n (%) | 9 (14) | 5 (16) | 10 (12) | NS | | PCI history, n (%) | 15 (23) | 7 (23) | 49 (61) |
(1) vs. (3)
(2) vs. (3) | | CABG history, n (%) | 4 (6) | 2 (7) | 8 (10) | NS |
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ASA: acetylsalicylic acid, WBC: white blood cells, RBC: red blood cells, PCI: percutaneous coronary intervention, CABG: coronary artery bypass grafting, Hb: hemoglobin, SD: standard deviation, and NS: no statistical significance ( value above 0.05). |
