High-Sensitivity Cardiac Troponin T Is a Risk Factor for Major Adverse Cardiovascular Events and All-Cause Mortality: A 9.5-Year Follow-Up Study

Table 3

Cox proportional hazards models analysis for associations between baseline hs-cTnT levels and outcomes.

	Mace		Coronary event		All-cause mortality
	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value
Unjust	1.313 (1.144–1.506)	<0.001	1.747 (1.440–2.210)	<0.001	1.996 (1.470–2.709)	<0.001
Model1	1.188 (1.026–1.375)	0.021	1.395 (1.122–1.734)	0.003	1.472 (1.025–2.115)	0.036
Model2	1.183 (1.016–1.377)	0.030	1.392 (1.110–1.746)	0.004	1.657 (1.145–2.397)	0.007
Model3	1.223 (1.054–1.418)	0.008	1.391 (1.106–1.749)	0.005	1.763 (1.224–2.540)	0.002

Models are defined as follows: model 1 = adjusted for age and gender; model 2 = adjusted for model 1 + presence of hypertension or diabetes mellitus, current smoking status, systolic blood pressure, postprandial blood glucose, total cholesterol, high-density lipoprotein cholesterol, antihypertensive medication use, and antidiabetic medication use; model 3 = adjusted for model 2 + estimated glomerular filtration rate; model 4 = adjusted for model 3 + high-sensitivity C-reactive protein and N-terminal pro-B-type natriuretic peptide (both after logarithmic transformation). MACE, major adverse cardiovascular event.