Cardiovascular Organ Damage in Clinical Subtypes of Systemic Sclerosis: Arterial Stiffness and Echocardiography Might Not Be the Ideal Tools for Patient Risk Stratification

Table 1

Clinical characteristics of the SSc study population.

	All	Diffuse	Limited
N	41	21 (51.2)	20 (48.8)
Age	56.9 ± 13.6	51.7 ± 12.7	62.4 ± 12.5	0.009^#
Female (%)	35 (85.3)	17 (81)	18 (90)	0.66^$
Smokers	11 (26.8)	4	7	0.35^$
Weight (kg)	62.3 ± 10.6	64.5 ± 11.4	59.9 ± 9.4	0.17^#
BMI (kg/m^2)	24.4 ± 3.7	24.9 ± 3.9	23.8 ± 3.5	0.35^#
SBP (mmHg)	118 ± 17.3	115.9 ± 16.2	121.2 ± 18.3	0.33^#
DBP(mmHg)	69.7 ± 8.6	70.7 ± 7.7	68.6 ± 9.5	0.44^#
HR (bpm)	75 ± 9.7	77.2 ± 9.8	72.9 ± 9.4	0.16^#
Past medical history
Alcohol	8 (19.5)	4 (19)	4 (20)	1^$
HTN	11 (26.7)	6 (28.6)	5 (25)	1^$
Hx of HTN	26 (63.4)	12 (57.1)	14 (70)	0.5^$
Dyslipidemia	8 (19.5)	4(19)	4 (20)	1^$
Hx of dyslipidemia	14 (34.1)	7 (33.3)	7 (35)	1^$
DM	1 (0.02)	1 (0.05)	0
Hx of DM	12 (29.3)	7 (30)	5 (25)	0.73^$
SSc-specific parameters
Disease duration (months)	81 [46; 130]	60 [34–94]	88 [67; 130]	0.13^$
Autoantibodies
ANA	39 (95.1)	19 (90.5)	20 (100)	0.48^$
Scl70	14 (34.1)	14 (66.7)	0	<0.001^$
Anticentromere	20 (48.8)	0	20 (100)	<0.001^$
Clinical features
Acral ulcers	15 (36.6)	11 (52.4)	4 (20)	0.051^$
Pulmonary fibrosis	22 (53.6)	15	7	0.006^$
Renal crisis	1 (0.02)	1 (0.05)	0
Hypotonia	31 (83.8)	17 (81)	14 (70)	0.67^$
Positive capillaroscopy	22 (54)	15 (71.4)	7 (35)	0.054^$